Cetuximab is a recombinant chimeric monoclonal antibody that binds to the extracelluar domian of the human epidermal growth factor receptor, and it was used for the treatment of metastatic colorectal cancer, metastatic non-small cell lung cancer and head and neck cancer. The antibody derived from Cetuximab without the glycosylation of galactose-alpha-l,3-galactose which has ben shown to cause allergic responses in some patient.
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