Anti-Human CD4 Therapeutic Antibody (Priliximab)

Recombinant monoclonal antibody to CD4. Priliximab (cMT 412) is a human-mouse chimeric anti-CD4 monoclonal antibody. It has been tested on patients with Crohn's disease and multiple sclerosis but has not yet received U.S. Food and Drug Administration licencing.

Specifications

Immunogen
P815 mastocytoma ce11stransfected with human CD4 cDNA

Host Species
Mouse

Derivation
Chimeric (mouse/human)

Type
IgG1 - kappa

Specificity
Tested positive against native human antigen.

Species Reactivity
Human

Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.

Trade name
centara

CAS
147191-91-1

Generic Name
Priliximab

Related Disease
Crohn's disease (CD)

Target

Alternative Names
Priliximab;centara;147191-91-1;cM-T412;M-T412;CEN 000029;MT 412;cMT 412;cMT 412;CD4;CD4 molecule;CD4 antigen (p55) , T cell surface glycoprotein CD4;T-cell surface glycoprotein CD4;CD4 receptor;CD4 antigen (p55);T-cell surface antigen T4/Leu-3;CD4mut;

Gene ID
920

UniProt ID
P01730

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Resources

See other products for "Priliximab"

See other products for "CD4"

3D IHC3D Immunohistochemistry

ActivActivation

AgonistAgonist

ApopApoptosis

BABioassay

BIBioimaging

BlockBlocking

Cell ScreeningCell Screening

SeparationCell Separation

ChIPChromatin Immunoprecipitation

CMCDComplement Mediated Cell Depletion

CostimCostimulation

CytCytotoxicity

DepletionDepletion

DBDot Blot

EMElectron Microscopy

ELISAEnzyme-linked Immunosorbent Assay

ELISPOTEnzyme-linked Immunosorbent Spot

FCFlow Cytometry

FuncSFunctional Assay

GSGel Super Shift Assay

HAHemagglutination

IAImmunoassay

IBImmunoblotting

ICCImmunocytochemistry

IDImmunodiffusion

IFImmunofluorescence

IHCImmunohistochemistry

IHC-FrImmunohistochemistry-Frozen

IHC-PImmunohistochemistry-Paraffin

REImmunohistology - Resin Sections

IPImmunoprecipitation

IRMAImmunoradiometric Assay

SHIn situ hybridization

InhibInhibition

ICFCIntracellular Staining for Flow Cytometry

KO/KD-WBKnockout/Knockdown target confirmation by Western Blot

Live cell imagingLive cell imaging

CyTOF®Mass Cytometry

MeDIPMethylated DNA Immunoprecipitation

MultiplexMultiplex bead-based assay

NeutNeutralization

PPProtein Purification

PGProteogenomics

RIRadial Immunodiffusion

RIARadioimmunoassay

StimStimulation

SPRSurface Plasmon Resonance

TCTissue Culture

TBTurbidimetry

WBWestern Blot

Anti-Human CD4 Therapeutic Antibody (Priliximab)