Anti-Human MS4A1 Therapeutic Antibody (H2L10) (CAT#: TAB-1685CL)

This fully human anti-CD20 monoclonal antibody has excellent affinity and specificity, and a significant cytotoxic effect on lymphoma cells, and so can be used for the preparation of pharmaceutical compositions for treating or diagnosing diseases such as non-Hodgkin lymphoma, B cell lymphoma, rheumatic and rheumatoid diseases, systemic lupus erythematosus, immune thrombocytopenic purpura and multiple sclerosis.

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CDC

Figure 1 The results of CDC test of Raji cells.

The purification of human antibodies H2L3, H2L6, H2L10, H8L3 by CHO cells after affinity maturation. And CDC functional screening of H8L10;

ADCC

Figure 2 The results of ADCC test of Raji cells.

A representation of purified human antibodies H2L3, H2L6, H2L10 for CHO cells after affinity maturation. ADCC functional screening of H8L3 and H8L10;


Specifications

  • Immunogen
  • CD20 protein
  • Host Species
  • Human
  • Type
  • Fully human antibody
  • Specificity
  • Human
  • Clone
  • H2L10
  • Applications
  • ADCC, CDC
  • Related Disease
  • Non-Hodgkin lymphoma, B cell lymphoma, rheumatic and rheumatoid diseases, systemic lupus erythematosus, immune thrombocytopenic purpura and multiple sclerosis

Applications

  • Application Notes
  • This antibody has been tested for use in Antibody-dependent Cellular Cytotoxicity Assay and Complement-dependent Cytotoxicity Assay.

Target

  • Alternative Names
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-1

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

See other products for "MS4A1"

See other products for "Clone H2L10"


For Research Use Only. Not For Clinical Use.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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