This fully human anti-CD20 monoclonal antibody has excellent affinity and specificity, and a significant cytotoxic effect on lymphoma cells, and so can be used for scientific researches of all kinds of diseases such as non-Hodgkin lymphoma, B cell lymphoma, rheumatic and rheumatoid diseases, systemic lupus erythematosus, immune thrombocytopenic purpura and multiple sclerosis.
Figure 1 ADCC test results of Raji cells against antibodies A137, H2L10 and rituximab.
Figure 2 The results of CDC testing of Raji cells by antibodies A137 and rituximab.
Figure 3 The results of orthotopic transplantation of A137 and rituximab in the treatment of human B cell lymphoma mouse raji cells.
Each mouse was intravenously injected with 10⁷ Raji lymphoma cells to form a mouse invasive lymphoma disease model, and administered intraperitoneally 5 days later. Experiments were performed in 3 groups of mice (8 per group): A. saline control group; B. rituximab group (dose 1 mg/kg body weight); C. A137 group (dose 1 mg/kg body weight).
Figure 4 A graph showing changes in body weight of mice treated with A137 and rituximab in the treatment of human B cell lymphoma mouse raji cells orthotopically transplanted tumors.
Each mouse was intravenously injected with 10⁷ Raji lymphoma cells to form a mouse invasive lymphoma disease model, and administered intraperitoneally 5 days later. Experiments were performed in 4 groups of mice (8 per group): A. saline control group; B. rituximab high dose group (3 mg/kg body weight); C. rituximab low dose group (1 mg/kg body weight); 0. 137 groups (1 mg/kg body weight). detailed description
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-913-sdAb | Recombinant Anti-human MS4A1 VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
HPAB-M0704-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD25) | ELISA, FuncS | Camelid VHH |
HPAB-M0705-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD16) | ELISA | Camelid VHH |
HPAB-M0706-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone R3CD7) | ELISA | Camelid VHH |
HPAB-M0707-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD78) | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-772 | Human Anti-MS4A1 Recombinant Antibody (TAB-772) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 |
TAB-771 | Humanized Anti-MS4A1 Recombinant Antibody (TAB-771) | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized IgG1, κ |
TAB-1638CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) | ADCC, CDC | Humanized IgG |
TAB-1639CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) | ADCC, CDC, Apop | Humanized IgG |
TAB-1640CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1640CL) | ADCC, CDC, Apop, FuncS | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-419 | Human Anti-MS4A1 Recombinant Antibody (clone 2F2); Fab Fragment | WB, ELISA, FuncS | Human Fab |
PFBL-420 | Mouse Anti-MS4A1 Recombinant Antibody (clone GA101); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
PSBZ-143 | Mouse Anti-MS4A1 Recombinant Antibody (clone KM3575); scFv Fragment | WB | Mouse scFv |
FAMAB-0241CQ-F(E) | Mouse Anti-MS4A1 Recombinant Antibody (clone 2H7); Fab Fragment | ELISA, FC, IHC, IP | Mouse Fab |
HPAB-0819-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone 1F5RKF12); Fab Fragment | ELISA, FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0001CL | Human Anti-MS4A1 Recombinant Antibody (TAB-0001CL) | ELISA, ADCC, CDC | Human IgG |
TAB-1674CL-S(P) | Anti-Human MS4A1 Recombinant Antibody scFv Fragment (101) | Cyt, ELISA, FuncS, Inhib | |
TAB-1676CL-S(P) | Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1676CL-S(P)) | ELISA | Human scFv |
TAB-1693CL-S(P) | Anti-MS4A1 Recombinant Antibody scFv Fragment | ELISA | |
TAB-1703CL-S(P) | Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1703CL-S(P)) | FC, CDC, IP | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1632CL-S(P) | Anti-Human MS4A1 Recombinant Antibody scFv Fragment (1F5) | FC | |
TAB-1632CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1F5) | FC | |
TAB-1657CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1K1422) | Apop, FuncS | |
TAB-1658CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1K1791) | Apop, FuncS | |
PABX-026-S (P) | Recombinant Mouse Anti-CD20 Antibody scFv Fragment (C2H7) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1665CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1665CL-F(E)) | CDC | Chimeric (mouse/human) Fab |
TAB-1666CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1666CL-F(E)) | CDC | Chimeric (mouse/human) Fab |
TAB-1667CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1667CL-F(E)) | CDC | Chimeric (mouse/human) Fab |
TAB-1668CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1668CL-F(E)) | CDC | Chimeric (mouse/human) Fab |
TAB-1669CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1669CL-F(E)) | CDC | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-060LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Gly-063LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
Gly-067LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA, FC | Chimeric antibody (mouse/human) |
Gly-097LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
Gly-158LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-063LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
Gly-134LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-135LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-136LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-137LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-142LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-155LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-171LC | Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0279MZ | Mouse Anti-MS4A1 Recombinant Antibody (clone M27 (1, 4).) | IHC | Mouse IgG2a |
FAMAB-0241CQ | Mouse Anti-MS4A1 Recombinant Antibody (clone 2H7) | ELISA, FC, IHC, IP | Mouse IgG2b, κ |
HPAB-0819-CN | Human Anti-MS4A1 Recombinant Antibody (clone 1F5RKF12) | ELISA, FC | Humanized IgG |
HPAB-0820-CN | Human Anti-MS4A1 Recombinant Antibody (clone RHAxRKF12) | ELISA, FC | Humanized IgG |
HPAB-0465LY | Mouse Anti-MS4A1 Recombinant Antibody (clone CBL004LY) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC066 | PE-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC067 | APC-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC068 | BV421-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC4347 | PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1751CQ | Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) | Neut, FuncS | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2295 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone DS2295AB) | IHC-Fr, IHC-P | Rabbit IgG |
MOR-4024 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone SI88DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-772 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-016 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-028 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-207 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-771 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1584-FY-F(E) | Mouse Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1584-FY-F(E)) | ELISA, FC | Mouse Fab |
HPAB-1585-FY-F(E) | Mouse Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1585-FY-F(E)) | ELISA, FC | Mouse Fab |
HPAB-J0043-YC-S(P) | Mouse Anti-MS4A1 Recombinant Antibody (clone 13.6E12); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
HPAB-1885-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1885-FY-F(E)) | ELISA, FC | Human Fab |
HPAB-1954-FY-S(P) | Human Anti-MS4A1 Recombinant Antibody (clone BD31-7); scFv Fragment | Cyt | Humanized scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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