Human Anti-CD28 Antibody (TGN1412), CHO Stable Cell Pool

Name: Human Anti-CD28 Antibody (TGN1412), CHO Stable Cell Pool
SKU: VS-1025-QX327
Rating: 5 (1 reviews)

CAT#: VS-1025-QX327

This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant TGN1412. TGN1412 is a Human monoclonal antibody that targets CD28. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of TGN1412 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.

Gene Expression

Normal Tissue Figure 1 Lymph node

Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70003/161787_A_9_8.jpg

Normal Tissue Figure 2 Tonsil

Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70003/161787_A_6_8.jpg

RNA Expression Figure 3 RNA cell line category: Group enriched (Karpas-707, RPMI-8226, U-266/70, U-266/84)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000178562-CD28

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Specifications

Host Cell
CHO

Product Type
Stable Cell Pool

Cell Viability
>90%

Mycoplasma Detection
Negative

Bacteria Detection
Negative

Growth Properties
Suspension

Culture Medium
VersaCHO™ Medium (VS-1025-QX582)

Complete Growth Medium
VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)

Freeze Medium
90% VersaCHO™ Medium, 10% DMSO

Growth Conditions
37°C, 5% CO₂

Size
Each vial contains at least 1×10^6 cells in 1 mL

Shipping
Dry ice

Storage
Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.

Antibody Overview

Host Species
Human

Antibody Type
Human IgG4, κ

Clone
TGN1412

Target
CD28

Species Reactivity
Human

Target

Alternative Names
Tp44; CD28

Gene ID
940

UniProt ID
P10747

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Related Diseases

Rheumatoid Arthritis

Systemic Lupus Erythematosus

Allograft Rejection

Autoimmune Thyroid Disease

Graft-versus-Host Disease

Maturity Onset Diabetes of the Young

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Datasheet

Datasheet - VS-1025-QX327.pdf

MSDS

MSDS - VS-1025-QX327.pdf

COA

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