Anti-Human CD28 Recombinant Antibody Fab Fragment (TGN1412) (CAT#: TAB-064LC-F(E))

TAB-064LC is a superagonistic monoclonal antibody (mAb) capable of fully activating T-cells by cross-linking CD28 molecules, even without signal 1, which sets it apart from conventional anti-CD28 mAbs. TAB-064LC-F(E) antibody is the Fab fragment antibody form of TAB-064LC antibody. Fab fragments, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • TGN1412
  • Applications
  • FC
  • Related Disease
  • Inflammatory diseases, Autoimmune diseases

Target

  • Alternative Names
  • Tp44; CD28

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Ideal for T-cell Activation
TGN1412 has greatly facilitated our research into T-cell activation. Its specific targeting of CD28 has provided consistent and reliable results in our in vitro assays.

Flow Cytometry Compatible
Using TGN1412 in flow cytometry has provided detailed insights into T-cell subsets. Its binding to CD28 has facilitated precise analysis of activation markers in our studies.

Insightful Cytokine Production Studies
Using TGN1412 to stimulate T-cells has provided comprehensive insights into cytokine production. Our cytokine assays consistently show reproducible and significant results.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-064LC-F(E), RRID: AB_3111786)

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