Mouse Anti-CD4 Recombinant Antibody (clone M-T310) (CAT#: FAMAB-0054YC)
The product recognizes an epitope on the CD4 molecule, a co-receptor for the T-cell receptor (TCR). This antibody possesses a CD4 binding affinity of 8.2 nM.
Specific Inquiry
ACTIV
Figure 1 Mouse Anti-CD4 Antibody (clone M-T310) in ACTIV.
Activation of human complement by anti-CD4 mAb. Deposition of complement components C3c, C4 and C5 is shown as total fluorescence mean channel after detection by C3-, C4- and C5-specific FITC-conjugated antisera in a FACscan analysis; a, m M-T151 (IgG2a); b, m M-T310 (IgG1); c,m M-T151+m M-T310; d,chim M-T151 (IgG1); e, chim M-T310 (IgG1); f, chim M-T151+chim M-T310.
Weissenhorn, W., Scheuer, W., Kaluza, B., Schwirzke, M., Reiter, C., Flieger, D., ... & Weidle, U. H. (1992). Combinatorial functions of two chimeric antibodies directed to human CD4 and one directed to the α-chain of the human interleukin-2 receptor. Gene, 121(2), 271-278.
Northern blot
Figure 2 Mouse Anti-CD4 Antibody (clone M-T310) in Northern blot.
Northern blot analysis of hybridomas and transfectomas secreting murine and chimeric mAb M-T151 and M-T310.
Weissenhorn, W., Scheuer, W., Kaluza, B., Schwirzke, M., Reiter, C., Flieger, D., ... & Weidle, U. H. (1992). Combinatorial functions of two chimeric antibodies directed to human CD4 and one directed to the α-chain of the human interleukin-2 receptor. Gene, 121(2), 271-278.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human CD4
- Species Reactivity
- Human
- Clone
- M-T310
- Applications
- Neut
- Related Disease
- AIDS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Primary Immunodeficiency
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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|---|---|---|---|
| TAB-039 | Anti-Human CD4 Recombinant Antibody (Zanolimumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG1 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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