Human Anti-MS4A1 Recombinant Antibody (clone Rmut8) (CAT#: HPAB-0683-CN)

The monoclonal antibody Rmut8 is derived from rituximab comprising H57DE/H102YK/L93NR mutations. Rmut8 shows strongly enhanced ADCC activity than Rituximab. The tumor killing effect of Rmut8 is significantly higher than Rituximab.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric (mouse/human) IgG
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • Rmut8
  • Applications
  • ELISA, FC
  • Related Disease
  • Wegener's Granulomatosis (WG), Microscopic Polygamiitis (MPA), in combination with glucocorticoides

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains, Subfamily A, Member 1; Leukocyte Surface Antigen Leu-16; CD20 Antigen; CD20; Bp35; Membrane-Spanning 4-Domains Subfamily A Member 1; B-Lymphocyte Cell-Surface Antigen B1; B-Lymphocyte Surface Antigen B1;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Rmut8"

See other products for "MS4A1"

Chimeric Antibody

CAT Product Name Application Type
TAB-207 Anti-Human CD20 Recombinant Antibody ELISA, IP, FC, FuncS, Neut, IF, ICC IgG1 - kappa
TAB-1633CL-S(P) Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5) FC Chimeric antibody (mouse/human)
TAB-1634CL-S(P) Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5-DXL) FC, Apop, CDC, ADCC, Inhib Chimeric antibody (mouse/human)
TAB-1633CL-F(E) Anti-Human MS4A1 Recombinant Antibody Fab Fragment (ch1F5) FC Chimeric antibody (mouse/human)
TAB-1665CL-F(E) Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1665CL-F(E)) CDC Chimeric (mouse/human) Fab

Humanized Antibody

CAT Product Name Application Type
TAB-133 Anti-Human CD20 Recombinant Antibody (Afutuzumab) IP, IF, FuncS, FC, Neut, ELISA, ICC IgG3 - kappa
TAB-537CL Human Anti-MS4A1 Recombinant Antibody (TAB-537CL) ELISA Human IgG
TAB-1638CL Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) ADCC, CDC Humanized IgG
TAB-1639CL Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) ADCC, CDC, Apop Humanized IgG
TAB-1640CL Human Anti-MS4A1 Recombinant Antibody (TAB-1640CL) ADCC, CDC, Apop, FuncS Humanized IgG

Recombinant Antibody

Fc Glycosylation

Hyper-galactosylated

High-mannose Glycoform

CAT Product Name Application Type
Gly-155LC-1 Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-171LC Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) ELISA Chimeric antibody (mouse/human)

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1751CQ Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) Neut, FuncS Mouse IgG1, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-772 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-016 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-028 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-207 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-771 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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