Rabbit Anti-TFPI Recombinant Antibody (clone R07-6A6)
CAT#: VS3-FY2092
The anti-Tissue factor pathway inhibitor antibody detected positive in western blot analysis of TFPI in A549, HL-60, U2OS lysates. The recombinant monoclonal antibody has been meticulously designed to target human TFPI. It is suitable for use in a variety of assays, including WB, IP. This R07-6A6 antibody is validated for western blot analysis of TFPI in A549, HL-60, U2OS lysates.
Gene Expression
Tested Data
Normal Tissue
Figure 1 IHC staining of human smooth muscle
Immunohistochemical staining of human smooth muscle shows distinct positivity in endothelial.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5575/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows distinct cytoplasmic positivity in endothelium.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells Staining: High Intensity: Strong Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25% Peripheral nerve/ganglion Staining: Low Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_7_3.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Decidual cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HHSteC, HUVEC TERT2, LHCN-M2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003436-TFPI
❮
❯
WB
Figure 1 Anti-TFPI Antibody (VS3-FY2092) in WB.
The TFPI expression in A549, HL-60, U2OS lysates were detected using the anti-TFPI by western blot assay.
❮
❯
Specifications
- Immunogen
- Recombinant human TFPI protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human TFPI
- Species Reactivity
- Human
- Clone
- R07-6A6
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 35 kDa, while the observed molecular weight stands at 40-55 kDa.
- Related Disease
- Willebrand's disease
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Tissue Factor Pathway Inhibitor; Extrinsic Pathway Inhibitor; Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor); TFPI1; LACI; EPI; Lipoprotein-Associated Coagulation Inhibitor; Anti-Convertin; TFI
- Gene ID
- 7035
- UniProt ID
- P10646
- Cellular Localization
- Endoplasmic reticulum, Membrane, Microsome, Secreted
- Post Translation Modifications
- O-glycosylated.
- Protein Refseq
- NP_001027452.1; NP_001305870.1; NP_001316168.1
- Function
- Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS3-FY2092. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "TFPI"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-734 | Anti-TFPI Recombinant Antibody (Concizumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-711 | Human Anti-TFPI Recombinant Antibody (clone mAb 2021); scFv Fragment | Block | Human scFv |
| HPAB-0428-YC-S(P) | Human Anti-TFPI Recombinant Antibody (clone TFPI-106); scFv Fragment | ELISA, FC, FuncS | Human scFv |
| HPAB-0429-YC-S(P) | Human Anti-TFPI Recombinant Antibody (clone TFPI-118); scFv Fragment | ELISA, FC, FuncS | Human scFv |
| HPAB-0431-YC-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0431-YC-S(P)) | ELISA, FC | Mouse scFv |
| PSBC-461 | Mouse Anti-TFPI Recombinant Antibody; scFv Fragment (PSBC-461) | ELISA, FC, Neut | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3547 | Rabbit Anti-TFPI Recombinant Antibody (clone DS3547AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-461 | Mouse Anti-TFPI Recombinant Antibody; Fab Fragment (PFBC-461) | ELISA, FC, Neut | Mouse Fab |
| HPAB-2587LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2587LY-F(E)) | ELISA, WB, FuncS | Human Fab |
| HPAB-2588LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2588LY-F(E)) | ELISA, WB, FuncS | Human Fab |
| HPAB-2589LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2589LY-F(E)) | ELISA, WB, FuncS | Human Fab |
| HPAB-2590LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2590LY-F(E)) | ELISA, WB, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-734 | Afuco™ Anti-TFPI ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-734) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2598LY | Human Anti-TFPI Recombinant Antibody (HPAB-2598LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2599LY | Human Anti-TFPI Recombinant Antibody (HPAB-2599LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2600LY | Human Anti-TFPI Recombinant Antibody (HPAB-2600LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2601LY | Human Anti-TFPI Recombinant Antibody (HPAB-2601LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2602LY | Human Anti-TFPI Recombinant Antibody (HPAB-2602LY) | ELISA, WB, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC647 | AbPlus™ Anti-TFPI Magnetic Beads (VS-0724-YC647) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY189 | Human Anti-TFPI (clone Concizumab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7198 | Anti-TFPI Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC305 | Recombinant Anti-TFPI Eliminating Antibody, pH-Sensitive (VS-0625-YC305) | Antigen-Sweeping In Vivo. | Human IgG4 kappa |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, FC, IF, IHC, WB
Application: ELISA, FC, Neut, Inhib
Application: FC
Application: ELISA, Cyt, PP, Inhib
Application: ELISA, Neut, FuncS
Application: IF, ICC, WB, IHC-P, IP
Application: ELISA, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
