Mouse Anti-TH Recombinant Antibody (clone 1B8D2) (CAT#: VS7-0425-WR979)
This product is a mouse IgG1 antibody that binds to human TH. The antibody 1B8D2 recognizes specific amino acid domain of human TH (AA: 44-208). It can be used for WB, IHC, ICC, and FC assays. It cross reacts with rat.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14010/1905_B8_3_selected.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14010/1905_B8_3_selected.jpg
Figure 2 High expression in adrenal gland
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61003/159875_B_6_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61003/159875_B_6_5_val_selected.jpg
Figure 3 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61003/160099_A_3_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61003/160099_A_3_3_val_selected.jpg
Figure 4 RNA cell line category: Group enriched (PC-3, SK-BR-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000180176-TH
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000180176-TH
Specifications
- Immunogen
- Recombinant human TH (AA: 44-208) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human TH
- Species Reactivity
- Human, Rat
- Clone
- 1B8D2
- Molecule Class
- Tyrosine Hydroxylase
- Applications
- WB, IHC, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Segawa syndrome autosomal recessive (ARSEGS)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Immunocytochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- TH; EC 1.14.16; Dystonia 14; Tyrosine 3-Hydroxylase; EC 1.14.16.2; Tyrosine 3-Monooxygenase; DYT5b; TYH; Tyrosine Hydroxylase; DYT14
- Gene ID
- 7054
- UniProt ID
- P07101
- Long Name
- Tyrosine Hydroxylase
- Cellular Localization
- Cell projection; Cytoplasm; Cytoplasmic vesicle; Nucleus; Synapse
- Post Translation Modifications
- Phosphoprotein
- Protein Refseq
- NP_000351.2
- Function
- Monooxygenase; Oxidoreductase
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Related Resources
Amphetamine Addiction
Alcoholism
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2042z | Mouse Anti-TH Recombinant Antibody (clone 26H11) | WB, ICC, IF | Mouse IgG2a |
| MRO-1545-CN | Rabbit Anti-TH Recombinant Antibody (clone CBACN-567) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-CJ456 | Rabbit Anti-TH Recombinant Antibody (VS3-CJ456) | WB, ICC, IHC, FC | Rabbit IgG |
| VS3-FY1925 | Rabbit Anti-TH Recombinant Antibody (clone R01-3E4) | WB, IHC-Fr, IHC-P, IF | Rabbit IgG |
| VS3-WK1590 | Mouse Anti-TH Recombinant Antibody (clone 4B1) | IHC-P, WB | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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