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    Human Anti-TNFRSF17 Recombinant Antibody (clone UniAb)

    CAT#: VS-0724-YC37

    The product is a human heavy chain-only antibody UniAb targeting human BCMA. UniAb was generated in transgenic rats that produce chimeric HCAbs with fully human VH domains in response to an antigen challenge. The thermostability of UniAb was analyzed by differential scanning calorimetry (DSC). The Tm values of the VH domains ranged from 59.1°C to 66.8°C.

    Gene Expression
    ❮
    Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, U-266/70, U-266/84)
    ❯

    Specifications

    • Immunogen
    • Recombinant BCMA protein
    • Host Species
    • Human
    • Derivation
    • Hybridoma
    • Type
    • Heavy chain only antibody (HCAb)
    • Specificity
    • Human TNFRSF17 (also known as BCMA)
    • Species Reactivity
    • Human
    • Clone
    • UniAb
    • Applications
    • ELISA

    Product Property

    • Purification
    • Protein A purified
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis
    • Buffer
    • PBS, pH 7.4
    • Preservative
    • No preservatives
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • BCM; BCMA; CD269; TNFRSF13A
    • Long Name
    • TNF receptor superfamily member 17
    • Cellular Localization
    • Cell membrane; Single-pass type III membrane protein
      Endomembrane system; Single-pass type III membrane protein
      Note: Perinuclear Golgi-like structures.
    • Post Translation Modifications
    • Glycosylation at Asn42.
    • Function
    • Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
      Promotes B-cell survival and plays a role in the regulation of humoral immunity.
      Activates NF-kappa-B and JNK.
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    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - VS-0724-YC37.pdf

    MSDS

    MSDS - VS-0724-YC37.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

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