Human Anti-TNFRSF17 Recombinant Antibody (clone UniAb) (CAT#: VS-0724-YC37)

The product is a human heavy chain-only antibody UniAb targeting human BCMA. UniAb was generated in transgenic rats that produce chimeric HCAbs with fully human VH domains in response to an antigen challenge. The thermostability of UniAb was analyzed by differential scanning calorimetry (DSC). The Tm values of the VH domains ranged from 59.1°C to 66.8°C.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Specifications

  • Immunogen
  • Recombinant BCMA protein
  • Host Species
  • Human
  • Derivation
  • Hybridoma
  • Type
  • Heavy chain only antibody (HCAb)
  • Specificity
  • Human TNFRSF17 (also known as BCMA)
  • Species Reactivity
  • Human
  • Clone
  • UniAb
  • Applications
  • ELISA

Product Property

  • Purification
  • Protein A purified
  • Purity
  • >95% as determined by SDS-PAGE and SEC-HPLC analysis
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • BCM; BCMA; CD269; TNFRSF13A
  • Long Name
  • TNF receptor superfamily member 17
  • Cellular Localization
  • Cell membrane; Single-pass type III membrane protein
    Endomembrane system; Single-pass type III membrane protein
    Note: Perinuclear Golgi-like structures.
  • Post Translation Modifications
  • Glycosylation at Asn42.
  • Function
  • Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
    Promotes B-cell survival and plays a role in the regulation of humoral immunity.
    Activates NF-kappa-B and JNK.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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