Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
+ Filter
Loading...
Custom Services order now ship next day

CD274

Hexamer Antibody Products AbPlus Recombinant Antibody Products Functional Antibody Products Formats

Anti-Cd274 Recombinant Antibody Products

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


CD274, also known as PD-L1 (Programmed Death-Ligand 1), is a gene that encodes a transmembrane protein involved in immune regulation. PD-L1 is primarily expressed on antigen-presenting cells, including dendritic cells, macrophages, and B cells, as well as on non-immune tissues, particularly under inflammatory conditions. This protein plays a critical role in immune evasion by interacting with PD-1 (Programmed Cell Death Protein 1), an inhibitory receptor expressed on T cells. The PD-L1/PD-1 interaction suppresses T-cell activation, reducing immune responses against tumors and infections. Overexpression of PD-L1 is often observed in cancers, allowing them to escape immune surveillance. As a result, PD-L1 inhibitors, such as monoclonal antibodies, have become a major focus in cancer immunotherapy, effectively restoring T-cell function and enhancing antitumor immunity.
Cd274
  • 0
  • 0
Cart
    Inquiry
    Go to compare

    Go to compare