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    Rat Anti-PDCD1 Recombinant Antibody (HPAB-0526-FY) (CAT#: HPAB-0526-FY)

    This product is a rat recombinant monoclonal antibody binding to canine PD1 (cPD1). The antibody was derived from a hybridoma cell line that secretes a cPD1-specific monoclonal antibody. It could inhibit the binding between hPDL1-cPD1 and cPD1-cPDL1. The product was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3528/1899_B9_6_cr5ba2049576272_selected.jpg
    Figure 2 IF staining of human cell line BJ
    Figure 2 IF staining of human cell line BJ
    (Immunofluorescent staining of human cell line BJ shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3528/1936_G3_3_blue_red_green.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3528/1953_G5_3_blue_red_green.jpg
    Normal Tissue
    Figure 4 Colon
    Figure 4 Colon
    (Peripheral nerve/ganglion
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76385/169546_A_9_3.jpg
    Figure 5 Placenta
    Figure 5 Placenta
    (Cytotrophoblasts
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Syncytiotrophoblasts - cell body
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Syncytiotrophoblasts - microvilli
    Staining:High
    Intensity: Strong)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76385/169546_A_1_7.jpg
    RNA Expression
    Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HHSteC, U-251 MG)
    Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HHSteC, U-251 MG)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120217-CD274

    Specifications

    • Host Species
    • Rat
    • Type
    • Rat IgG2a
    • Specificity
    • Canine PDCD1
    • Species Reactivity
    • Canine
    • Applications
    • Inhib
    • Related Disease
    • Cancer

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • CD279; PD1; Programmed cell death protein 1; HPD-1; HSLE1
    • Long Name
    • Programmed death protein 1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Cd274"

    Select a product category from the dropdown menu below to view related products.
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    CAT Product Name Application Type
    PFBL-298 Human Anti-CD274 Recombinant Antibody (clone CBLC-006); Fab Fragment WB, ELISA, FuncS Human Fab
    HPAB-0933LY-F(E) Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0933LY-F(E)) Inhib, ELISA Human Fab
    HPAB-0934LY-F(E) Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0934LY-F(E)) Inhib, ELISA Human Fab
    HPAB-0935LY-F(E) Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0935LY-F(E)) Inhib, ELISA Human Fab
    HPAB-0936LY-F(E) Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0936LY-F(E)) Inhib, ELISA Human Fab

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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