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EGFR & doxorubicin
Loading...Anti-EGFR & doxorubicin Products
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IL2-IgG2a
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, WB
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- Derivation: Chimeric
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG2 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
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- Derivation: Humanized (from rat)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB
- Mouse Anti-EGFR Recombinant Antibody (TAB-271MZ) (TAB-271MZ)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FuncS
- Anti-Human EGFR Recombinant Antibody (ABT-806) (TAB-228CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
- Application: WB, IHC
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- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, WB, Inhib
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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- Derivation: Chimeric (Human/Mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, FC, IF, IHC, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, FuncS
- Human Anti-EGFR Recombinant Antibody (TAB-272MZ) (TAB-272MZ)
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FuncS
- Human Anti-EGFR Recombinant Antibody (TAB-0225CL) (TAB-0225CL)
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human
- Type: Chimeric (Mouse/Human) IgG1
- Application: Block, Inhib, FuncS, Apop, In vivo
- Human Anti-EGFR Recombinant Antibody (TAB-274MZ) (TAB-274MZ)
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-EGFR Recombinant Antibody (TAB-282MZ) (TAB-282MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, FuncS, Inhib
- Human Anti-EGFR Recombinant Antibody (TAB-283MZ) (TAB-283MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, FuncS, Inhib
- Human Anti-EGFR Recombinant Antibody (TAB-284MZ) (TAB-284MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-EGFR Recombinant Antibody (TAB-278MZ) (TAB-278MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, ELISA, Inhib
- Human Anti-EGFR Recombinant Antibody (TAB-279MZ) (TAB-279MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, ELISA, Inhib
- Human Anti-EGFR Recombinant Antibody (TAB-287MZ) (TAB-287MZ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ADCC assay
- Human Anti-EGFR Recombinant Antibody (TAB-288MZ) (TAB-288MZ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ADCC assay
- Human Anti-EGFR Recombinant Antibody (TAB-289MZ) (TAB-289MZ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ADCC assay
- Human Anti-EGFR Recombinant Antibody (TAB-290MZ) (TAB-290MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Block, Cyt, ELISA, FC, FuncS, Inhib
- Rabbit Anti-Human EGFR (phospho Y1092) Antibody (MOB-0242MC)
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- Species Reactivity: Rat, Human
- Application: IHC, WB
- Rabbit Anti-Human EGFR (phospho Y1068) Antibody (MOB-0243MC)
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- Species Reactivity: Human, Mouse, Rat
- Application: IHC, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: Block
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-270MZ-S(P)) (TAB-270MZ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-274MZ-S(P)) (TAB-274MZ-S(P))
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-272MZ-S(P)) (TAB-272MZ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-278MZ-S(P)) (TAB-278MZ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-279MZ-S(P)) (TAB-279MZ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-0225CL-S(P)) (TAB-0225CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Block, Inhib, FuncS, Apop, In vivo
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-282MZ-S(P)) (TAB-282MZ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-281MZ-S(P)) (TAB-281MZ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IF, IHC
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-273MZ-S(P)) (TAB-273MZ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-275MZ-S(P)) (TAB-275MZ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
- Anti-Human EGFR Recombinant Antibody scFv Fragment (LA1) (TAB-276MZ-S(P))
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- Application: MTT assay
- Anti-Human EGFR Recombinant Antibody scFv Fragment (LA22) (TAB-277MZ-S(P))
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- Application: MTT assay
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-271MZ-S(P)) (TAB-271MZ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: Block
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
- Anti-EGFR Antibody-Cytokine Fusion Protein, IgG-IL2 (ACFP-SH155)
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL2
- Mouse Anti-EGFR Recombinant Antibody (TAB-281MZ) (TAB-281MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IF, IHC
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-0564CL-S(P)) (TAB-0564CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-0565CL-S(P)) (TAB-0565CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-EGFR Recombinant Antibody (TAB-285MZ) (TAB-285MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FuncS
- Mouse Anti-EGFR Recombinant Antibody (TAB-286MZ) (TAB-286MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FuncS
- Mouse Anti-EGFR Recombinant Antibody (TAB-275MZ) (TAB-275MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Cyt, FuncS, Inhib
- Anti-Human EGFR Recombinant Antibody (LA1) (TAB-276MZ)
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- Application: Cyt, FuncS
- Anti-Human EGFR Recombinant Antibody (LA22) (TAB-277MZ)
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- Application: Cyt, FuncS
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: TNFα
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: TNF-IgG2a
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB, FuncS
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, WB, FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, FuncS
- Mouse Anti-EGFR Recombinant Antibody (TAB-273MZ) (TAB-273MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, FuncS, IHC, IP, Inhib
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Mouse-Human)
- Cytokine 1 Species: Human
- Molecule Class: IgG-IL2
- 10-FnIII scaffold protein anti-Human EGFR (SFN-L003)
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- Scaffold Name: 10-FnIII
- Target: EGFR
- Species Reactivity: Human
- Derivation: Phage display
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- Scaffold Name: Z-domain of protein A
- Target: EGFR
- Species Reactivity: Human
- Derivation: Phage display
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- Species Reactivity: Mouse
- Type: Llama VHH
- Application: ELISA, IHC, FC, FuncS
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- Targets: EGFR & doxorubicin
- Type: CrossMab
- Application: FuncS, Pretargeting system for therapic agent delivery
- Anti-EGFR (clone Bat0206)-S-3AA-MDC ADC (ADC-157CL)
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- Target: EGFR
- Linker: S-3AA
- Drug: MDC (maytansinol)
- Anti-EGFR (clone Bat0206)-SMCC-MDC ADC (ADC-158CL)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: MDC (maytansinol)
- Anti-EGFR-vc-PAB-MODO ADC (ADC-263CL)
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- Target: epidermal growth factor receptor (EGFR)
- Linker: VC-PAB (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MODO (monomethyldolastatin)
- Anti-EGFR-Mal-dPEG4-NHS-DM1 ADC (ADC-107LCT)
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- Target: EGFR
- Linker: Mal-dPEG4-NHS
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-EGFR (MAb806)-Mc-MMAF ADC (ADC-109LCT)
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- Target: EGFR
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-EGFR (MAb806)-SMCC-DM1 ADC (ADC-110LCT)
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- Target: EGFR variant III
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-EGFR-doxorubicin ADC (ADC-168LZY)
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- Target: EGFR
- Linker: polyethylene glycol linker
- Drug: doxorubicin
- Anti-EGFR-MC-VC-PABA-MMAE ADC (ADC-037CL)
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- Target: EGFR
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-EGFR-MC-VC-PABA-MMAE ADC (ADC-038CL)
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- Target: EGFR
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-EGFR-mc-MMAF ADC (ADC-039CL)
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- Target: EGFR
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-EGFR (clone Antibody 1)-MC-MMAF ADC (ADC-059CL)
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- Target: EGFR
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Doxorubicin (ADCsR-026CL)
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- Formula: C27H29NO11
- CAS No.: 23214-92-8
- Anti-EGFR (clone J2898A)-SMCC-DM1 ADC (ADC-047LZY)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-EGFRvIII-SMCC-DM1 ADC (ADC-048LZY)
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- Target: EGFRvIII
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-EGFR (clone ABT-806)-mc-MMAF ADC (ADC-071LZY)
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- Target: EGFR
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-EGFR-vc-Duostatin-3 ADC (ADC-088LZY)
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- Target: EGFR
- Linker: VC (valine-citrulline)
- Drug: Duostatin-3
- Anti-EGFR-SMCC-methotrexate ADC (ADC-059LZY)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: MTX
- Anti-EGFR-MCC-Dox ADC (ADC-057LZY)
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- Target: EGFR
- Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
- Drug: doxorubicin
- Anti-EGFR (ABT-806)-Mc-MMAE ADC (ABT-414) (ADC-L001)
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- Target: EGFR
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-EGFR (J2898A)-SMCC-DM1 ADC (IMGN289) (ADC-L016)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto- 1-oxopropyl)maytansine)
- Anti-EGFR-EDC/NHS-Dox ADC (ADC-058LZY)
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- Target: EGFR
- Linker: EDC/NHS(1-ethyl-3-(3-diaminopropyl)carbodiimide/N-hydroxysuccinimide)
- Drug: doxorubicin
- Anti-EGFR-EDC/NHS-methotrexate ADC (ADC-060LZY)
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- Target: EGFR
- Linker: EDC/NHS
- Drug: MTX
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For Research Use Only. Not For Clinical Use.
Background
Doxorubicin is a medication used in cancer chemotherapy. It is derived by chemical semisynthesis from a bacterial species.
Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin. Isoform 2 may act as an antagonist of EGF action.


Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
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Cushing Syndrome
JAK-STAT Signaling Pathway
