Anti-Human EGFR Recombinant Antibody (LA22) (CAT#: TAB-277MZ)
This monoclonal antibody LA22 that can specifically bind to EGFR can be conjugated with a cytotoxic agent for treating cancers.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 demonstrates the cytotoxic effects of anti-EGFR monoclonal antibodies conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.
Figure 2 illustrates the dose-dependent cytotoxic effect of monoclonal antibody LA22 conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.
Figure 3 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate, MMC and naked mAb LA22 on A431 cells.
Figure 4 illustrates the in vivo tumor toxicity effect of LA22-MMC on female Balb/c mice.
Figure 5 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate on human epidermoid carcinoma cells.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- LA22
- Applications
- Cyt, FuncS
- Related Disease
- Cancers such as glioblastoma or cancer of the lung, breast, head and neck, and bladder
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity, Functional Assay.
Target
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
- Gene ID
- 1956
- UniProt ID
- P00533
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone LA22"
See other products for "EGFR"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-165 | Anti-Human EGFR Recombinant Antibody (Matuzumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 |
TAB-710 | Anti-EGFR Recombinant Antibody (Nimotuzumab) | ELISA, IP, FC, FuncS, Neut, IF, IHC | IgG1 - kappa |
TAB-274MZ | Human Anti-EGFR Recombinant Antibody (TAB-274MZ) | FC | Humanized IgG |
TAB-297MZ | Anti-Human EGFR Recombinant Antibody (H225) | ELISA, WB | Humanized antibody |
PABX-051-S (P) | Recombinant Mouse Anti-EGFR Antibody scFv Fragment (Matuzumab) | WB, Neut, FuncS | scFv |
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For Research Use Only. Not For Clinical Use.
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