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    Anti-Human EGFR Recombinant Antibody (LA22) (CAT#: TAB-277MZ)

    This monoclonal antibody LA22 that can specifically bind to EGFR can be conjugated with a cytotoxic agent for treating cancers.

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    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    Purity :
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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Cyt

    Figure 1 demonstrates the cytotoxic effects of anti-EGFR monoclonal antibodies conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.

    Figure 1 demonstrates the cytotoxic effects of anti-EGFR monoclonal antibodies conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.

    FuncS

    Figure 2 illustrates the dose-dependent cytotoxic effect of monoclonal antibody LA22 conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.

    Figure 2 illustrates the dose-dependent cytotoxic effect of monoclonal antibody LA22 conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.

    Cyt

    Figure 3 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate, MMC and naked mAb LA22 on A431 cells.

    Figure 3 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate, MMC and naked mAb LA22 on A431 cells.

    FuncS

    Figure 4 illustrates the in vivo tumor toxicity effect of LA22-MMC on female Balb/c mice.

    Figure 4 illustrates the in vivo tumor toxicity effect of LA22-MMC on female Balb/c mice.

    FuncS

    Figure 5 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate on human epidermoid carcinoma cells.

    Figure 5 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate on human epidermoid carcinoma cells.


    Specifications

    • Host Species
    • Mouse
    • Specificity
    • Human
    • Clone
    • LA22
    • Applications
    • Cyt, FuncS
    • Related Disease
    • Cancers such as glioblastoma or cancer of the lung, breast, head and neck, and bladder

    Applications

    • Application Notes
    • This antibody has been reported for use in Cytotoxicity, Functional Assay.

    Target

    • Alternative Names
    • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone LA22"

    See other products for "EGFR"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Humanized Antibodies Human Antibodies Single Domain Antibodies Chimeric Antibodies Mouse Antibodies Fc Glycosylation Antibodies High-mannose Glycoform Antibodies Deglycosylated Antibodies Chicken IgY Antibodies MHC Tetramers for Cancer Neutralizing Antibodies Rabbit Monoclonal Antibodies IgG Antibodies Fab Antibodies ScFv Antibodies ADCC Enhanced Antibodies Antibody Magnetic Beads Cancer Stem Cell Biomarker Specific Antibodies NHP Antibodies ScFv-Fc Chimeras FC Reagents & Kits IHC Kits & Antibodies Extracellular Vesicle Antibodies Biparatopic Antibodies
    CAT Product Name Application Type
    TAB-165 Anti-Human EGFR Recombinant Antibody (Matuzumab) Neut, ELISA, IF, IP, FuncS, FC, ICC IgG1
    TAB-710 Anti-EGFR Recombinant Antibody (Nimotuzumab) ELISA, IP, FC, FuncS, Neut, IF, IHC IgG1 - kappa
    TAB-274MZ Human Anti-EGFR Recombinant Antibody (TAB-274MZ) FC Humanized IgG
    TAB-297MZ Anti-Human EGFR Recombinant Antibody (H225) ELISA, WB Humanized antibody
    PABX-051-S (P) Recombinant Mouse Anti-EGFR Antibody scFv Fragment (Matuzumab) WB, Neut, FuncS scFv

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