Anti-Human EGFR Recombinant Antibody (LA22) (CAT#: TAB-277MZ)
This monoclonal antibody LA22 that can specifically bind to EGFR can be conjugated with a cytotoxic agent for treating cancers.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Cyt
Figure 1 demonstrates the cytotoxic effects of anti-EGFR monoclonal antibodies conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.
FuncS
Figure 2 illustrates the dose-dependent cytotoxic effect of monoclonal antibody LA22 conjugated with pingyangmycin or mitomycin C on human epidermoid carcinoma cells.
Cyt
Figure 3 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate, MMC and naked mAb LA22 on A431 cells.
FuncS
Figure 4 illustrates the in vivo tumor toxicity effect of LA22-MMC on female Balb/c mice.
FuncS
Figure 5 shows the in vitro cytotoxic effect of LA22-MMC immunoconjugate on human epidermoid carcinoma cells.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- LA22
- Applications
- Cyt, FuncS
- Related Disease
- Cancers such as glioblastoma or cancer of the lung, breast, head and neck, and bladder
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity, Functional Assay.
Target
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
- Gene ID
- 1956
- UniProt ID
- P00533
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
JAK-STAT Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone LA22"
See other products for "EGFR"
Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products
Chimeric Antibody Products
Human Antibody Products
Mouse Antibody Products
Fc Glycosylation Antibody Products
High-mannose Glycoform Antibody Products
Deglycosylated Antibody Products
Chicken IgY Antibody Products
MHC Tetramer Products for Cancer
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
ADCC Enhanced Antibody Products
Fab Antibody Products
IgG Antibody Products
Single Domain Antibody Products
Antibody Magnetic Beads
Cancer Stem Cell Biomarker Specific Antibody Products
Non-Human Primate (NHP) Antibody Products
ScFv-Fc Chimera Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-165 | Anti-Human EGFR Recombinant Antibody (Matuzumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 |
| TAB-274MZ-S(P) | Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-274MZ-S(P)) | FC | Humanized scFv |
| TAB-297MZ-S(P) | Anti-Human EGFR Recombinant Antibody scFv Fragment (H225) | ELISA, WB | Humanized antibody |
| TAB-298MZ-S(P) | Anti-Human EGFR Recombinant Antibody scFv Fragment (Hu225) | ELISA, WB | Humanized antibody |
| TAB-300MZ-S(P) | Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-300MZ-S(P)) | ELISA | Humanized scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-277MZ. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
-2.png)
-2.png)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: Block, IP, IF, FC
Application: ELISA, Inhib, FC, Neut
Application: ELISA, WB, Microarray, Block
Application: ELISA, FC, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
