STAT5A

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and phosphate ion binding activity. Involved in growth hormone receptor signaling pathway via JAK-STAT and regulation of growth. Acts upstream of with a positive effect on taurine metabolic process. Acts upstream of or within several processes, including positive regulation of leukocyte proliferation; regulation of hemopoiesis; and reproductive structure development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in colon adenocarcinoma.