Humanized Anti-MS4A1 Recombinant Antibody (TAB-771) (CAT#: TAB-771)

Ocrelizumab is a humanized monoclonal antibody that selectively targets CD20-positive B cells, resulting in antibody-dependent cellular cytolysis, antibody-dependent cellular phagocytosis, apoptosis, and/or complement-mediated lysis of the B cells.


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  • Gene Expression
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FC

Figure 1 Anti-CD20 Antibody (TAB-771) in Flow Cytometry

Figure 1 Anti-CD20 Antibody (TAB-771) in Flow Cytometry

Flow cytometry analysis of Daudi cells with Anti-CD20 Antibody (Cat#TAB-771, Blue line) or isotype control antibody (Yellow line). A Goat Anti-human IgG (FITC) was used as the secondary antibody.

WB

Figure 2 Anti-CD20 Antibody (TAB-771) in WB

Figure 2 Anti-CD20 Antibody (TAB-771) in WB

Western blot analysis of TAB-771 was performed with CD20 Protein, Human, Recombinant (TrxA Tag).
TAB-771 incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing Antigen (0.6μg)


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • Humanized IgG1, κ
  • Specificity
  • Human MS4A1
  • Species Reactivity
  • Human
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC, ICC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • B1; S7; Bp35; CD20; CVID5; LEU-16; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; membrane-spanning 4-domains, subfamily A, member 1

Related Resources

  • Biosimilar Overview
Please refer to Ocaratuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ocaratuzumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "MS4A1"

Humanized Antibody

Recombinant Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-1656CL Anti-Human MS4A1 Recombinant Antibody (ch2B8) FC, CMCD, ADCC, Activ, Inhib, Depletion Chimeric antibody (mouse/human)
TAB-1656CL-S(P) Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch2B8) FC, CMCD, ADCC, Activ, Inhib, Depletion Chimeric antibody (mouse/human)
TAB-1665CL-F(E) Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1665CL-F(E)) CDC Chimeric (mouse/human) Fab
TAB-1666CL-F(E) Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1666CL-F(E)) CDC Chimeric (mouse/human) Fab
TAB-1667CL-F(E) Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1667CL-F(E)) CDC Chimeric (mouse/human) Fab

Fc Glycosylation

Hyper-galactosylated

High-mannose Glycoform

CAT Product Name Application Type
Gly-155LC-1 Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-171LC Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) ELISA Chimeric antibody (mouse/human)

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1751CQ Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) Neut, FuncS Mouse IgG1, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-772 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-016 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-028 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-207 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-771 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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