Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
  • Home
  • EGFR
  • Mouse Anti-EGFR Recombinant Antibody (clone L211C); Fab Fragment

Mouse Anti-EGFR Recombinant Antibody (clone L211C); Fab Fragment (CAT#: HPAB-0010-YC-F(E))

Epidermal growth factor (EGF) is a polypeptide hormone which is mitogenic for epidermal and epithelial cells. When EGF interacts with sensitive cells, it binds to membrane receptors (EGFR). The EGFR is a transmembrane glycoprotein of about 170 kD and is a gene product of the c-erb-B proto-oncogene. The anti-EGFR antibodies can be used as agents for the diagnosis and therapy of human tumors.

See more Engineered Antibody products for EGFR
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg
Normal Tissue
Figure 3 Colon
Figure 3 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg
Figure 7 Placenta
Figure 7 Placenta
(Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity:>75%
Decidual cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enriched (A-431)
Figure 9 RNA cell line category: Cell line enriched (A-431)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR

Specifications

  • Host Species
  • Mouse
  • Derivation
  • Phage display library
  • Type
  • Mouse Fab
  • Specificity
  • Human EGFR
  • Species Reactivity
  • Human
  • Clone
  • L211C
  • Applications
  • ELISA, FC
  • Related Disease
  • Tumor

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Epidermal Growth Factor Receptor 2; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian); Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog; Cell Proliferation-Inducing Protein 61; Cell Growth Inhibiting Protein 40; EC 2.7.10; NISBD2; PIG61; MENA

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone L211C"

See other products for "EGFR"

Select a product category from the dropdown menu below to view related products.
Please select product type
Chimeric Antibody Single-domain Antibody Human Antibody Humanized Antibody Mouse Antibody Fc Glycosylation High-mannose Glycoform Deglycosylated Antibody (Non-glycosylated IgGs) Chicken IgY Antibody MHC Tetramer for Cancer Neutralizing Antibody Rabbit Monoclonal Antibody Fab Fragment Antibody Recombinant Antibody ADCC Enhanced Antibody scFv Fragment Antibody
CAT Product Name Application Type
TAB-750 Anti-EGFR/HER1 Recombinant Antibody (Futuximab/Zatuximab) Neut, ELISA, IF, IP, FuncS, FC, WB IgG1 - kappa
TAB-0225CL Human Anti-EGFR Recombinant Antibody (TAB-0225CL) Block, Inhib, FuncS, Apop, In vivo Chimeric (Mouse/Human) IgG1
TAB-302MZ Human Anti-EGFR Recombinant Antibody (TAB-302MZ) ELISA Chimeric (mouse/human) IgG1
TAB-308MZ Human Anti-EGFR Recombinant Antibody (TAB-308MZ) FuncS Chimeric antibody (mouse/human)
PABX-051 Recombinant Human Anti-EGFR Antibody (Matuzumab) WB, Neut, FuncS, FC, ELISA, IF, Inhib IgG

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for HPAB-0010-YC-F(E). Click the button above to contact us or submit your feedback about this product.

Popular products with customers

Figure 1 Anti-KIRD2 Subgroup Antibody (Lirilumab) (TAB-757) in ELISA

Anti-KIRD2 Subgroup Recombinant Antibody (Lirilumab) (CAT# TAB-757)
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC

Figure 1 Anti-Human Frizzled receptor Antibody (TAB-880) in SDS-PAGE

Anti-Human Frizzled receptor Recombinant Antibody (Vantictumab) (CAT# TAB-880)
Application: Inhib, Cyt

Figure 1 Anti-PDCD1 Recombinant Antibody (TAB-770) in ELISA

Anti-PDCD1 Recombinant Antibody (Nivolumab) (CAT# TAB-770)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 1 Anti-Human CD79B Recombinant Antibody (TAB-897) in WB

Humanized Anti-CD79B Recombinant Antibody (clone Polatuzumab) (CAT# TAB-897)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 1 Anti-Human ERBB2 Recombinant Antibody (Pertuzumab) (TAB-053) in SPR

Anti-Human ERBB2 Recombinant Antibody (Pertuzumab) (CAT# TAB-053)
Application: FuncS, IF, Neut, ELISA, FC, IP, WB

Figure 1 Anti-Human CD30 Therapeutic Antibody (TAB-153) in ELISA

Chimeric (Mouse/Human) Anti-TNFRSF8 Recombinant Antibody (clone Brentuximab) (CAT# TAB-153)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 1 Anti-Human CD3 Therapeutic Antibody (TAB-019) in DB

Anti-Human CD3 Recombinant Antibody (Muromonab-CD3) (CAT# TAB-019)
Application: FC, IP, ELISA, Neut, FuncS, IF, WB

Figure 1 Anti-Human EPCAM Antibody (TAB-235CL) in ELISA

Human Anti-Human EPCAM Recombinant Antibody (3622W94) (CAT# TAB-235CL)
Application: Cyt, FC

Figure 2 Recombinant Human Anti-RSV Antibody (PABL-321) in HPLC

Recombinant Human Anti-RSV Antibody (AM14) (CAT# PABL-321)
Application: WB, ELISA, Neut, FuncS

Figure 1 Anti-RSV Antibody (PABL-322) in ELISA

Recombinant Human Anti-RSV Antibody (D25) (CAT# PABL-322)
Application: WB, ELISA, Neut, FuncS

Figure 1 Human Anti-TSHR Recombinant Antibody (PABL-737) in SDS-PAGE

Human Anti-TSHR Recombinant Antibody (clone K1-70) (CAT# PABL-737)
Application: Block

Figure 1 Anti-CD28 Antibody (TAB-064LC) in ELISA

Anti-Human CD28 Recombinant Antibody (TGN1412) (CAT# TAB-064LC)
Application: FC, Stim

Figure 1 Anti-Human DEspR Recombinant Antibody (TAB-190MZ) in SDS-PAGE

Anti-Human DEspR Recombinant Antibody (7C5B2) (CAT# TAB-190MZ)
Application: FC, FuncS, Inhib

Figure 1 Anti-FOLR1 Antibody (TAB-020CQ) in WB

Mouse Anti-FOLR1 Recombinant Antibody (TAB-020CQ) (CAT# TAB-020CQ)
Application: ELISA, FC, WB, IHC

Figure 3 Anti-Human MUC1 Antibody (TAB-428MZ) in Dot Blot

Mouse Anti-MUC1 Recombinant Antibody (TAB-428MZ) (CAT# TAB-428MZ)
Application: ELISA, IHC, FC, WB, IF, IA

Figure 1 Anti-Human SLC34A2 Recombinant Antibody (TAB-467MZ) in SDS-PAGE

Mouse Anti-SLC34A2 Recombinant Antibody (TAB-467MZ) (CAT# TAB-467MZ)
Application: FC, Inhib

Figure 1 Recombinant Human Anti-HCV E2 Antibody (HEPC74) (HPAB-0196CQ) in SDS-PAGE

Recombinant Human Anti-HCV E2 Antibody (HEPC74) (CAT# HPAB-0196CQ)
Application: ELISA, Neut

Figure 1 Mouse Anti-ανβ8 Recombinant Antibody (HPAB-N0303-YC) in WB

Mouse Anti-ανβ8 Recombinant Antibody (HPAB-N0303-YC) (CAT# HPAB-N0303-YC)
Application: ELISA, Block

Figure 1 Anti-DOTA Antibody (HPAB-1251WJ) in SDS-PAGE

Mouse Anti-DOTA Recombinant Antibody (HPAB-1251WJ) (CAT# HPAB-1251WJ)
Application: ELISA, Inhib

Figure 1 Mouse Anti-Anti-HIV-1 antibody VRC01 Anti-idiotype Antibody (PABJ-0191) in SDS-PAGE

Mouse Anti-Anti-HIV-1 antibody VRC01 Anti-idiotype Antibody (clone iv8) (CAT# PABJ-0191)
Application: ELISA, Vaccine, FuncS

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Inquiry
    Go to compare

    Go to compare