Recombinant Human Antibody (F5) is capable of binding to VEEV E2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-VEEV E2 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-VEEV E2 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Figure 1 Immunohistochemistry of Venezuelan equine encephalitis virus-infected mouse brains.
Virus antigen were detected in neurons from all areas of the CNS examined in an untreated mouse harvested at 5 days post-infection (PI) (A) or a mouse treated with hMAb F5 nIgG 24 h PI (B).
Hunt, A. R., Bowen, R. A., Frederickson, S., Maruyama, T., Roehrig, J. T., & Blair, C. D. (2011). Treatment of mice with human monoclonal antibody 24 h after lethal aerosol challenge with virulent Venezuelan equine encephalitis virus prevents disease but not infection. Virology, 414(2), 146-152.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-118 | Recombinant Rat Anti-HCV E2 Antibody (3/11) | WB, ELISA, Neut, FuncS | IgG |
PABL-119 | Recombinant Human Anti-HCV E2 Antibody (HC33.1) | Neut, FuncS | IgG |
PABL-120 | Recombinant Human Anti-HCV E2 Antibody (HC84-1) | WB, ELISA, Neut, FuncS | IgG |
PABZ-180 | Recombinant Mouse Anti-HCV E2 Antibody (mAb#8) | Neut | IgG |
PABZ-181 | Recombinant Human Anti-HCV E2 Antibody (hu5B3.v3) | ELISA, Neut | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-357 | Recombinant Human Anti-VEEV E2 Antibody scFv Fragment (F5) | WB, ELISA, Neut, FuncS | scFv |
PFBC-184 | Recombinant Chimeric (Human/Mouse) Anti-HCV glycoprotein E2 Antibody Fab Fragment (mAb1:7) | Neut | Fab |
HPAB-N0072-YC-S(P) | Recombinant Human Anti-E2 Antibody scFv Fragment (HC84.26.5D) | Neut, ELISA, FuncS | Human scFv |
HPAB-N0074-YC-S(P) | Recombinant Humanized Anti-E2 Antibody scFv Fragment (TRN-1008) | Neut, ELISA, WB | Humanized scFv |
HPAB-2105-FY-S(P) | Human Anti-E2 Recombinant Antibody (clone D12); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-119 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC33.1) | Neut, FuncS | Fab |
PFBL-120 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC84-1) | WB, ELISA, Neut, FuncS | Fab |
PFBL-121 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (HC84-27) | Neut, FuncS | Fab |
PFBL-122 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (mAb12) | WB, ELISA, FuncS | Fab |
PFBL-123 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (mAb8) | WB, Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PNBL-019 | Recombinant Anti-HCV E2 VHH Single Domain Antibody (D03) | Inhib, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-020CT | Human Anti-HCV E2 Recombinant Antibody (AP33) | ELISA, IP, Neut, FC, WB | Human antibody |
TAB-238CT | Anti-HCV E2 Recombinant Antibody (Y47F) | ELISA, WB | Human antibody |
TAB-239CT | Anti-HCV E2 Recombinant Antibody (Y47W) | ELISA, WB | Human antibody |
TAB-238CT-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (Y47F) | ELISA, WB | Human antibody |
TAB-239CT-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (Y47W) | ELISA, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YF094 | DRB1*03:01/HPV E2 (PIVQLQGDSNCLKCFR) MHC Monomer | MHC Multimer | |
MHC-YF095 | DRB1*03:01/HPV E2 (MEAIAKRLDACQDQLLELYE) MHC Monomer | MHC Multimer | |
MHC-YF1180 | PE-DRB1*03:01/Human E2 (MEAIAKRLDACQDQLLELYE) MHC Tetramer | FCM | |
MHC-YF1332 | FITC-DRB1*03:01/Human E2 (MEAIAKRLDACQDQLLELYE) MHC Tetramer | FCM | |
MHC-YF1345 | FITC-DRB1*03:01/Human E2 (PIVQLQGDSNCLKCFR) MHC Tetramer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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