Mouse Anti-CD28 Recombinant Antibody (clone 15E8) (CAT#: FN-121CQ)

• Versatile Research Tool
  The 15E8 antibody's versatility in combination with other antibodies has allowed us to explore complex immune interactions, making it an indispensable tool in our immunology research.
• Robust TCR Signaling Analysis
  The 15E8 antibody has been essential for studying TCR signaling. The co-stimulatory signals provided by CD28 engagement have clarified how these pathways function in T-cell activation.
• Suitable for Autoimmune Research
  The 15E8 antibody has been instrumental in our research on autoimmune diseases. It's helped us explore how CD28 signaling influences autoimmune T-cell activity, providing valuable insights.

1. Q 1: How is the research of T-cell receptor (TCR) signaling aided by the 15E8 clone?

   A: By engaging CD28, the 15E8 clone provides the necessary co-stimulatory signal alongside TCR engagement, enabling detailed studies on how co-stimulation influences TCR signaling pathways.

2. Q 2: What benefits does the 15E8 clone have for immunological research compared to other CD28 antibodies?

   A: The 15E8 clone offers high specificity and affinity for mouse CD28, and its recombinant nature ensures consistent performance across experiments, making it a reliable tool for immune studies.

3. Q 3: Is it possible to investigate how CD28 signaling affects T-cell differentiation using the 15E8 antibody?

   A: Yes, the 15E8 antibody's engagement of CD28 provides insights into how co-stimulatory signals influence T-cell differentiation into various subsets, such as Th1, Th2, or Treg cells.

View the frequently asked questions answered by Creative Biolabs Support.