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  • Human Anti-CD74 Recombinant Antibody (VS-0723-WK70)

Human Anti-CD74 Recombinant Antibody (VS-0723-WK70) (CAT#: VS-0723-WK70)

This product is a chimeric (rabbit/human) IgG1 antibody that recognizes human CD74, which is an important chaperone that regulates antigen presentation for immune response. This antibody is recommended for flow cytometry at a dilution of 1:100.


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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/if_selected.jpg
Figure 2 IHC staining of human spleen
Figure 2 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong granular cytoplasmic positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10592/ihc_selected.jpg
Figure 3 IHC staining of human tonsil
Figure 3 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79994/170659_A_6_8_selected.jpg
Figure 4 IF staining of human cell line U-251 MG
Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/203_F11_1_blue_red_green.jpg
Normal Tissue
Figure 5 Colon
Figure 5 Colon
(Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_7_3.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_5.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_8.jpg
Figure 8 Tonsil
Figure 8 Tonsil
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_6_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)
Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000019582-CD74

Specifications

  • Immunogen
  • Recombinant human CD74 protein
  • Host Species
  • Human
  • Derivation
  • Chimeric (rabbit/human)
  • Type
  • Chimeric (rabbit/human) IgG1
  • Specificity
  • Human CD74
  • Species Reactivity
  • Human
  • Applications
  • FC
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A purified
  • Purity
  • >95%
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 1×PBS
  • Preservative
  • No Preservative
  • Storage
  • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • Flow Cytometry: 1/100

Target

  • Alternative Names
  • DHLAG; HLADG; Ia-GAMMA; II; p33
  • Long Name
  • CD74 Molecule

Recommended Products

Isotype Control

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CD74"

Human Antibody

CAT Product Name Application Type
TAB-139CL Human Anti-CD74 Recombinant Antibody (TAB-139CL) ELISA Human IgG
TAB-0569CL Human Anti-CD74 Recombinant Antibody (TAB-0569CL) IHC, WB Human IgG
TAB-0570CL Human Anti-CD74 Recombinant Antibody (TAB-0570CL) ELISA, FC Human IgG
TAB-0571CL Human Anti-CD74 Recombinant Antibody (TAB-0571CL) ELISA, FC Human IgG
TAB-0572CL Human Anti-CD74 Recombinant Antibody (TAB-0572CL) ELISA, FC Human IgG

Single-domain Antibody

CAT Product Name Application Type
TAB-0004CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0004CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0005CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0005CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0006CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0006CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0007CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0007CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
TAB-0008CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0008CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH

Recombinant Antibody

CAT Product Name Application Type
MOB-0454MZ Recombinant Mouse Anti-Human CD74 Antibody (clone MO3 (Xpsltipq JW) (pvs eftjhobujpo 349)) ICC, IHC-Fr, IHC-P, WB Mouse antibody
VS3-XY404 Mouse Anti-CD74 Recombinant Antibody (clone 2D1B11) ELISA, WB, FC Mouse IgG1
VS3-XY405 Mouse Anti-CD74 Recombinant Antibody (clone 2D1B3) ELISA, WB, FC Mouse IgG1
VS3-XY406 Mouse Anti-CD74 Recombinant Antibody, FITC (clone 4ALN2) FC, IF Mouse IgG1
VS3-XY407 Mouse Anti-CD74 Recombinant Antibody, PE (clone 4ALN2) FC, IHC, IP, IF, WB Mouse IgG1

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1595 PE-DRB*01:01/Human CD74 (KPVSKMRMATPLLMQALPM) MHC Tetramer FCM
MHC-LC1598 PE-DRB*01:01/Human CD74 (KMRMATPLLMQALPM) MHC Tetramer FCM
MHC-LC1712 PE-DRB*01:01/Human CD74 (MKMRMATPLLMQALPM) MHC Tetramer FCM
MHC-LC1597 BV421-DRB*01:01/Human CD74 (KPVSKMRMATPLLMQALPM) MHC Tetramer FCM
MHC-LC1600 BV421-DRB*01:01/Human CD74 (KMRMATPLLMQALPM) MHC Tetramer FCM

Blocking Antibody

CAT Product Name Application Type
NEUT-408CQ Mouse Anti-CD74 Recombinant Antibody (clone LN2) FC, IHC-Fr, IHC-P, ICC, IP, WB, Block Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0579 Hi-Affi™ Rabbit Anti-CD74 Recombinant Antibody (clone DS579AB) ICC, IHC-P, IP, WB Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0388-FY-S(P) Human Anti-CD74 Recombinant Antibody; scFv Fragment (HPAB-0388-FY-S(P)) FC Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0388-FY-F(E) Human Anti-CD74 Recombinant Antibody; Fab Fragment (HPAB-0388-FY-F(E)) FC Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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