Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
  • Home
  • EGFR
  • Human Anti-EGFR Recombinant Antibody (clone E7.6.3); scFv Fragment

Human Anti-EGFR Recombinant Antibody (clone E7.6.3); scFv Fragment (CAT#: HPAB-S0022-YC-S(P))

There is provided a fully human monoclonal antibody against human epidermal growth factor receptor (EGF-r) that possess similar or enhanced activities as compared to antibody C225 in order to vitiate concerns and/or effects of HAMA or HACA response. The antibody secreted by the hybridoma E7.6.3 comprises a human IgG2 antibody having a human kappa light chain.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg
Normal Tissue
Figure 3 Colon
Figure 3 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg
Figure 7 Placenta
Figure 7 Placenta
(Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity:>75%
Decidual cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enriched (A-431)
Figure 9 RNA cell line category: Cell line enriched (A-431)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR

Specifications

  • Host Species
  • Human
  • Type
  • Human scFv
  • Specificity
  • Human EGFR
  • Species Reactivity
  • Human
  • Clone
  • E7.6.3
  • Applications
  • ELISA, Inhib, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian)

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone E7.6.3"

See other products for "EGFR"

Select a product category from the dropdown menu below to view related products.
Please select product type
Chimeric Antibody Products Humanized Antibody Products IgG Antibody Products ScFv Antibody Products Human Antibody Products Mouse Antibody Products Fc Glycosylation Antibody Products High-mannose Glycoform Antibody Products Deglycosylated Antibody Products Chicken IgY Antibody Products MHC Tetramer Products for Cancer Neutralizing Antibody Products Rabbit Monoclonal Antibody Products Fab Antibody Products ADCC Enhanced Antibody Products Single Domain Antibody Products Antibody Magnetic Beads Cancer Stem Cell Biomarker Specific Antibody Products Non-Human Primate (NHP) Antibody Products ScFv-Fc Chimera Products Flow Cytometry (FC) related Products
CAT Product Name Application Type
TAB-H35 Anti-Human EGFR Recombinant Antibody (Futuximab) IF, WB, Inhib IgG1 - kappa
TAB-272MZ Human Anti-EGFR Recombinant Antibody (TAB-272MZ) FuncS Chimeric (mouse/human) IgG
TAB-302MZ Human Anti-EGFR Recombinant Antibody (TAB-302MZ) ELISA Chimeric (mouse/human) IgG1
TAB-308MZ Human Anti-EGFR Recombinant Antibody (TAB-308MZ) FuncS Chimeric antibody (mouse/human)
PABX-051 Recombinant Human Anti-EGFR Antibody (Matuzumab) WB, Neut, FuncS, FC, ELISA, IF, Inhib IgG

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for HPAB-S0022-YC-S(P). Click the button above to contact us or submit your feedback about this product.

Popular products with customers

Figure 1 Anti-CD248 Recombinant Antibody (TAB-773) in SDS-PAGE

Anti-CD248 Recombinant Antibody (Ontuxizumab) (CAT# TAB-773)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 1 Recombinant Anti-5-FU Antibody (MOB-12) in ELISA

Recombinant Anti-5-FU Antibody (CAT# MOB-12)
Application: WB, Neut, FuncS

Figure 1 Anti-ErbB2 Antibody (TAB-005) in WB

Anti-Human ErbB2 Recombinant Antibody (TAB-005) (CAT# TAB-005)
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC

Figure 1 Anti-Human CD200 Recombinant Antibody (TAB-210) in SDS-PAGE

Anti-Human CD200 Recombinant Antibody (TAB-210) (CAT# TAB-210)
Application: IF, IP, Neut, FuncS, ELISA, FC, WB

Figure 1 Anti-Human IL13 Antibody (Tralokinumab) (TAB-218) in ELISA

Anti-Human IL13 Recombinant Antibody (Tralokinumab) (CAT# TAB-218)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 1 Anti-Human IL13 Recombinant Antibody (TAB-H05) in ELISA

Anti-Human IL13 Recombinant Antibody (Anrukinzumab) (CAT# TAB-H05)
Application: ELISA, Inhib

Figure 1 Anti-Human CSF2 Recombinant Antibody (TAB-H44) in WB

Anti-Human CSF2 Recombinant Antibody (TAB-H44) (CAT# TAB-H44)
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC

Figure 1 Anti-Human CD83 Recombinant Antibody (TAB-143CL) in SDS-PAGE

Anti-Human CD83 Recombinant Antibody (CAT# TAB-143CL)
Application:

Figure 1 Mouse Anti-EREG Recombinant Antibody (PABL-084) in SDS-PAGE

Mouse Anti-EREG Recombinant Antibody (clone 9E5) (CAT# PABL-084)
Application: ELISA, WB, FuncS

Figure 1 Anti-Human CEACAM5 Recombinant Antibody (PABL-496) in SDS-PAGE

Recombinant Mouse Anti-HCV E2 Antibody (AP33) (CAT# PABL-496)
Application: FC, Neut, FuncS

Figure 1 Mouse Anti-FCGR2B Antibody (TAB-036WM) in WB

Mouse Anti-FCGR2B Recombinant Antibody (TAB-036WM) (CAT# TAB-036WM)
Application: ELISA, FC, Inhib

Figure 1 Anti-Influenza A Virus (H1N1/H2N2) HA Recombinant Antibody (MRO-248LC) in SDS-PAGE

Anti-Influenza A Virus (H1N1/H2N2) HA Recombinant Antibody (C179) (CAT# MRO-248LC)
Application: ELISA

Figure 1 Anti-Human ANGPT2 Recombinant Antibody (TAB-0871CLV) in WB

Human Anti-ANGPT2 Recombinant Antibody (TAB-0871CLV) (CAT# TAB-0871CLV)
Application: SPR, Inhib, FuncS

Figure 1 Anti-RSV F Protein Antibody (MRO-2544CQ) in ELISA

Recombinant Mouse Anti-RSV F Protein Antibody (VC62) (CAT# MRO-2544CQ)
Application: ELISA, FC, IF, WB

Figure 1 Anti-SARS-CoV S Therapeutic Antibody (CR3022) (MRO-1214LC) in WB

Anti-SARS-CoV S Recombinant Antibody (MRO-1214LC) (CAT# MRO-1214LC)
Application: Neut, ELISA

Figure 1 Recombinant Anti-ICAM1 Single Domain Antibody (HPAB-0349-YC-VHH) in WB

Recombinant Llama Anti-ICAM1 Single Domain Antibody (HPAB-0349-YC-VHH) (CAT# HPAB-0349-YC-VHH)
Application: ELISA

Figure 1 Human Anti-FAP Recombinant Antibody (HPAB-0175-CN) in SDS-PAGE

Human Anti-FAP Recombinant Antibody (clone ESC14) (CAT# HPAB-0175-CN)
Application: ELISA, WB, FC, IHC, IP

Figure 1 Recombinant Anti-IL17A Antibody (HPAB-0208-LSX) in WB

Human Anti-IL17A Recombinant Antibody (HPAB-0208-LSX) (CAT# HPAB-0208-LSX)
Application: ELISA, FuncS

Figure 1 Mouse Anti-His Tag Recombinant Antibody; Fab Fragment (HPAB-0328-WJ-F(E)) in WB

Mouse Anti-His Tag Recombinant Antibody; Fab Fragment (HPAB-0328-WJ-F(E)) (CAT# HPAB-0328-WJ-F(E))
Application: ELISA, WB

Figure 1 Mouse Anti-MUC6 Recombinant Antibody (MOB-0118F) in IHC

Mouse Anti-MUC6 Recombinant Antibody (MOB-0118F) (CAT# MOB-0118F)
Application: IHC-P, IF

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Inquiry
    Go to compare

    Go to compare