Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone D40) (CAT#: MRO-4198CQ)
This product is a recombinant mouse anti-HIV-1 monoclonal antibody. D40 specifically binds to gp41.
Specific Inquiry
FC
Figure 1 Binding of MAbs to Env expressed on the surface of cells.
Env protein (cleaved gp160) was expressed on the surface of cells via recombinant vaccinia virus
vSC60.
Zhang, M. Y., Vu, B. K., Choudhary, A., Lu, H., Humbert, M., Ong, H., ... & Montefiori, D. C. (2008). Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. Journal of virology, 82(14), 6869-6879.
WB
Figure 2 Mapping of conformation-dependent MAbs by blocking.
The anti-gp41 linear MAbs were used as landmarks to map the regions of gp41 necessary for binding by conformation-dependent MAbs.
Zhang, M. Y., Vu, B. K., Choudhary, A., Lu, H., Humbert, M., Ong, H., ... & Montefiori, D. C. (2008). Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. Journal of virology, 82(14), 6869-6879.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Recognizes HIV-1 gp41
- Species Reactivity
- HIV-1
- Clone
- D40
- Applications
- WB, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp41 antibody has been reported in applications of Western Blot, Flow Cytometry.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone D40"
See other products for "HIV-1 gp41"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-486 | Recombinant Anti-HIV-1 gp41 Antibody | WB, Dot, FuncS | IgG |
| PABZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583) | Neut, FC | Mouse IgG2a, κ |
| MRO-859CQ | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 7H6) | ELISA | Human IgG1 |
| MRO-861CQ | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone A00020.01) | ELISA | Mouse IgG1 |
| MRO-862CQ | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone D1) | ELISA, WB | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-486-F(E) | Recombinant Human Anti-HIV-1 gp41 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| PFBL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583); Fab Fragment | Neut | Mouse Fab |
| PFBW-068 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D5); Fab Fragment | WB, ELISA | Human Fab |
| PFBC-069 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HK20); Fab Fragment | Neut, ELISA | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-025LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG3) | ELISA | Human antibody |
| MRO-026LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG1) | ELISA | Human antibody |
| MRO-040LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (M66.6) | ELISA | Human antibody |
| MRO-074LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (W) | ELISA | Human antibody |
| MRO-077LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (3D6) | ELISA | Human antibody |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-331 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-331) | Neut | Mouse scFv |
| PSBC-332 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8v4-5R+100cF); scFv Fragment | Neut | Human scFv |
| PSBC-334 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-334) | ELISA, Neut | Mouse scFv |
| PSBC-335 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-335) | ELISA, Neut | Mouse scFv |
| PSBC-336 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-336) | ELISA, Neut | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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