Human Anti-HIV-1 gp41 Recombinant Antibody (clone DN9) (CAT#: MRO-4068CQ)

Recombinant human antibody to gp41. DN9 specifically recognizes NHR coiled-coils that are unoccupied by peptide corresponding to the C-heptad repeat or CHR region of gp41 (e.g. C34).

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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We require custom production
  • Published Data
  • Datasheet
  • MSDS
  • COA
Neut

Figure 1 Presence of 10E8 alters sensitivity of HIV-1 to post-attachment fusion inhibitors.

Figure 1 Presence of 10E8 alters sensitivity of HIV-1 to post-attachment fusion inhibitors.

The neutralization sensitivity of cognate virus to DN9 IgG.

Kim, A. S., Leaman, D. P., & Zwick, M. B. (2014). Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization. PLoS pathogens, 10(7).


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • DN9
  • Applications
  • ELISA, Neut, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Neutralization, Functional Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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