Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H39)

Name: Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H39)
SKU: AFC-TAB-H39
Rating: 5 (1 reviews)

CAT#: AFC-TAB-H39

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Mouse antibody to Human MS4A1.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line REH

Immunofluorescent staining of human cell line REH shows localization to nucleoplasm & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/1778_G3_5_selected.jpg

Subcellular Location and Protein Expression Figure 2 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/201_H5_1_red_green.jpg

Subcellular Location and Protein Expression Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/202_H5_1_red_green.jpg

Normal Tissue Figure 4 Colon

Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_3.jpg

Normal Tissue Figure 5 Bone marrow

Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_B_4_4.jpg

Normal Tissue Figure 6 Lymph node

Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_8.jpg

RNA Expression Figure 7 RNA cell line category: Group enriched (Daudi, U-698)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000156738-MS4A1

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Specifications

Host Species
Mouse

Derivation
Mouse

Type
ADCC enhanced antibody

Specificity
MS4A1(membrane-spanning 4-domains subfamily A member 1, CD20) [Homo sapiens]

Species Reactivity
Human

Applications
FC, IP, ELISA, Neut, FuncS, IF

Conjugate
Unconjugated

Trade name
Zevalin

Generic Name
Ibritumomab

Related Disease
Non-Hodgkin's lymphoma (NHL)

Product Property

Purity
>95% by SDS-PAGE

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; MS4A2; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1; S7

Gene ID
931

UniProt ID
P11836

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-TAB-H39.pdf

MSDS

MSDS - AFC-TAB-H39.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "Ibritumomab"

Anti-Human CD20 Recombinant Antibody (Ibritumomab)
Recombinant monoclonal antibody to Human CD20. Ibritumomab tiuxetan, sold under the trade name Zevalin, is a monoclonal antibody radioimmunotherapy treatment for relapsed or refractory, low grade or transformed B cell non-Hodgkin's lymphoma, a lymphoproliferative disorder and thus affects the lymphatic system. The drug uses the monoclonal mouse IgG1 antibody ibritumomab (pronounced as < ih bri TYOO mo mab >) in conjunction with the chelator tiuxetan, to which a radioactive isotope (either yttrium-90 or indium-111) is added. Tiuxetan is a modified version of DTPA whose carbon backbone contains an isothiocyanatobenzyl and a methyl group

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HPAB-M0706-YC	Camelid Anti-MS4A1 Recombinant Antibody (HPAB-M0706-YC)	ELISA	Camelid VHH
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CAT	Product Name	Application	Type
TAB-016	Anti-Human CD20 Recombinant Antibody (Rituximab)	IF, IP, Neut, FuncS, ELISA, FC, WB	IgG1 - kappa
TAB-1633CL-S(P)	Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5)	FC	Chimeric antibody (mouse/human)
TAB-1634CL-S(P)	Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5-DXL)	FC, Apop, CDC, ADCC, Inhib	Chimeric antibody (mouse/human)
TAB-1656CL-S(P)	Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch2B8)	FC, CMCD, ADCC, Activ, Inhib, Depletion	Chimeric antibody (mouse/human)
PABX-026	Recombinant Human Anti-CD20 Antibody (C2H7)	FuncS	IgG

CAT	Product Name	Application	Type
TAB-017	Anti-Human CD20 Recombinant Antibody (TAB-017)	Neut, ELISA, IF, IP, FuncS, FC, ICC	IgG2a - lambda
TAB-711	Anti-MS4A1 Recombinant Antibody (Technetium (99MTC) Nofetumomab Merpentan)	FC, IP, ELISA, Neut, FuncS, IF, ICC	Fab - G2b - kappa
TAB-001	Anti-Human CD20 Recombinant Antibody (Ibritumomab)	ELISA, IP, FC, FuncS, IF, Neut	IgG1 - kappa
TAB-H27	Anti-Human MS4A1 Recombinant Antibody (Epitumomab)	IP, IF, FuncS, FC, Neut, ELISA, ICC	IgG2a
TAB-H39	Anti-Human MS4A1 Recombinant Antibody (Ibritumomab)	FC, IP, ELISA, Neut, FuncS, IF, ICC	Mouse IgG1 - kappa

CAT	Product Name	Application	Type
TAB-133	Anti-Human CD20 Recombinant Antibody (Afutuzumab)	IP, IF, FuncS, FC, Neut, ELISA, ICC	IgG3 - kappa
TAB-1635CL	Anti-Human MS4A1 Recombinant Antibody (BVX20)	Inhib	Humanized antibody
TAB-1636CL	Human Anti-MS4A1 Recombinant Antibody (TAB-1636CL)	ADCC, CDC	Humanized IgG
TAB-1637CL	Human Anti-MS4A1 Recombinant Antibody (TAB-1637CL)	ADCC, CDC	Humanized IgG
TAB-1638CL	Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL)	ADCC, CDC	Humanized IgG

CAT	Product Name	Application	Type
PABZ-143	Human Anti-MS4A1 Recombinant Antibody (clone KM3575)	WB	Chimeric (mouse/human) IgG1, κ
MOB-0279MZ	Mouse Anti-MS4A1 Recombinant Antibody (clone M27 (1, 4).)	IHC	Mouse IgG2a
MOB-027CQ	Human Anti-MS4A1 Recombinant Antibody (clone CBLS-185)	Neut, FuncS	Human IgG1, κ
HPAB-1693LY	Mouse Anti-MS4A1 Recombinant Antibody (HPAB-1693LY)	Neut, FC, IHC-Fr, IHC-P, IP	Mouse IgG
HPAB-1694LY	Human Anti-MS4A1 Recombinant Antibody (HPAB-1694LY)	Inhib	Humanized IgG

CAT	Product Name	Application	Type
TAB-1645CL	Anti-Human MS4A1 Recombinant Antibody (2.1.2)	Cyt, FuncS	Fully human antibody
TAB-1646CL	Anti-Human MS4A1 Recombinant Antibody (1.1.2)	Cyt, FuncS	Fully human antibody
TAB-1647CL	Anti-Human MS4A1 Recombinant Antibody (1.5.3)	Cyt, FuncS	Fully human antibody
TAB-1648CL	Anti-MS4A1 Recombinant Antibody (MEDI-552)	Inhib
TAB-1654CL	Human Anti-MS4A1 Recombinant Antibody (TAB-1654CL)	FC, Apop	Human IgG1, κ

CAT	Product Name	Application	Type
Gly-059LC	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation)	ELISA	Chimeric antibody (mouse/human)
Gly-063LC	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated)	ELISA	Chimeric antibody (mouse/human)
Gly-097LC	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation)	ELISA	Chimeric antibody (mouse/human)
Gly-115LC	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation)	ELISA	Humanized antibody
Gly-138LC	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
Gly-135LC-1	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated)	ELISA	Humanized antibody
Gly-136LC-1	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated)	ELISA	Humanized antibody
Gly-137LC-1	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated)	ELISA	Humanized antibody
Gly-138LC-1	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated)	ELISA	Humanized antibody
Gly-158LC-1	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated)	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
Gly-142LC-1	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Hyper-galactosylated)	ELISA	Human antibody

CAT	Product Name	Application	Type
Gly-155LC-1	Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
Gly-171LC	Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated)	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application
MHC-LC066	PE-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer	FCM
MHC-LC067	APC-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer	FCM
MHC-LC068	BV421-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer	FCM
MHC-LC4347	PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer	FCM

CAT	Product Name	Application	Type
NEUT-1751CQ	Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211)	Neut, FuncS	Mouse IgG1, κ

CAT	Product Name	Application	Type
MOR-2295	Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone DS2295AB)	IHC-Fr, IHC-P	Rabbit IgG
MOR-4024	Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone SI88DS)	FC	Rabbit IgG

CAT	Product Name	Application	Type
FAMAB-0241CQ-F(E)	Mouse Anti-MS4A1 Recombinant Antibody (clone 2H7); Fab Fragment	ELISA, FC, IHC, IP	Mouse Fab
HPAB-0465LY-F(E)	Mouse Anti-MS4A1 Recombinant Antibody (clone CBL004LY); Fab Fragment	ELISA	Mouse Fab
HPAB-0466LY-F(E)	Mouse Anti-MS4A1 Recombinant Antibody (clone CBL005LY); Fab Fragment	ELISA	Mouse Fab
HPAB-0247-FY-F(E)	Human Anti-MS4A1 Recombinant Antibody Fab Fragment (HPAB-0247-FY-F(E))	Inhib, ELISA	Humanized Fab
HPAB-0138-WJ-F(E)	Human Anti-MS4A1 Recombinant Antibody (clone L4H7); Fab Fragment	ELISA	Humanized Fab

CAT	Product Name	Application	Type
HPAB-0261CQ-S(P)	Mouse Anti-MS4A1 Recombinant Antibody (clone CBM502); scFv Fragment	ELISA, FC, FuncS	Mouse scFv
HPAB-0262CQ-S(P)	Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (HPAB-0262CQ-S(P))	ELISA, FC	Human scFv
HPAB-0264CQ-S(P)	Human Anti-MS4A1 Recombinant Antibody scFv Fragment (HPAB-0264CQ-S(P))	ELISA, FC	Human scFv
HPAB-1896LY-S(P)	Mouse Anti-MS4A1 Recombinant Antibody scFv Fragment (HPAB-1896LY-S(P))	ELISA, Inhib	Mouse scfv
HPAB-1897LY-S(P)	Human Anti-MS4A1 Recombinant Antibody scFv Fragment (HPAB-1897LY-S(P))	ELISA, Inhib	Chimeric scfv

CAT	Product Name	Application	Type
AFC-TAB-772	Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-772)	ELISA, IP, FC, FuncS, Neut, IF	ADCC enhanced antibody
AFC-TAB-016	Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-016)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody
AFC-TAB-028	Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-028)	FC, IP, ELISA, Neut, FuncS, IF	ADCC enhanced antibody
AFC-TAB-207	Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-207)	ELISA, IP, FC, FuncS, Neut, IF	ADCC enhanced antibody
AFC-TAB-771	Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-771)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0424-XY188	AbPlus™ Anti-MS4A1 Magnetic Beads (VS-0424-XY188)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0924-YC138	Human Anti-MS4A1 Recombinant Antibody Hexamer (VS-0924-YC138), CDC Enhanced	FC, CDC, IP	Antibody hexamer
VS-0924-YC139	Mouse Anti-MS4A1 Recombinant Antibody Hexamer (VS-0924-YC139), CDC Enhanced	FC, Activ, Agonist, IF, WB, Cyt, CDC	Antibody hexamer

CAT	Product Name	Application	Type
VS-1024-XY85	Mouse Anti-NHP MS4A1 Recombinant Antibody (VS-1024-XY85)	FC	Mouse IgG2b, kappa

CAT	Product Name	Application	Type
VS-0125-FY30	Human Anti-MS4A1 (clone RW005) scFv-Fc Chimera	FuncS	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0225-XY168	CytoStream™ Rat Anti-MS4A1 Recombinant Antibody (clone GOT214A)	FC	Rat IgG2a, kappa

CAT	Product Name	Application	Type
VS-0425-YC513	Recombinant Anti-MS4A1 Vesicular Antibody, EV Displayed (VS-0425-YC513)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY4510	Anti-MS4A1 Immunohistochemistry Kit	IHC
VS-0525-XY4511	Anti-Mouse MS4A1 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-YC129	Recombinant Anti-MS4A1 (Bin I x Bin II) Biparatopic Antibody, Tandem scFv	ELISA, FC	Tandem scFv
VS-0525-YC222	Recombinant Anti-MS4A1 Biparatopic Antibody, Tandem scFv	ELISA, IF, WB	Tandem scFv

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