Mouse Anti-PMEL Recombinant Soluble TCR (clone TIL 620/G9-209) (CAT#: scTCR-008YF-S(P))
Recombinant Mouse single-chain TCR (scTCR) TIL 620/G9-209 recognizes PMEL peptide (ITDQVPFSV) in the context of HLA-A*02:01. The scTCR is responsible for the specificity of T cells.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to endoplasmic reticulum & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/1898_C6_19_cr5ba8a6f6e250d_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to endoplasmic reticulum & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/1898_C6_19_cr5ba8a6f6e250d_selected.jpg
Figure 2 Kidney
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_A_7_5.jpg
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_A_7_5.jpg
Figure 3 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_A_4_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_A_4_6.jpg
Figure 4 Skin
(Melanocytes
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_B_7_1.jpg
(Melanocytes
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_B_7_1.jpg
Figure 5 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185664-PMEL
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185664-PMEL
Specifications
- Host Species
- Mouse
- Target
- PMEL
- Species Reactivity
- Human
- Epitope
- ITDQVPFSV
- MHC
- HLA-A*02:01
- Clone
- TIL 620/G9-209
- Type
- Single-Chain TCR
- Related Disease
- Melanoma
Target
- Alternative Names
- D12S53E, ME20, ME20-M, ME20M, P1, P10017, SI, SIL, SILV, gp100, PMEL
- Gene ID
- 6490
- UniProt ID
- P40967
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Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G051E | Anti-PMEL immunotoxin (Fab)-PE | Cytotoxicity assay, Function study |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1047CL | Anti-Human PMEL Recombinant Antibody (A3F) | WB | |
| TAB-1048CL | Anti-Human PMEL Recombinant Antibody (G11B) | WB, FC, IHC | |
| TAB-1049CL | Anti-Human PMEL Recombinant Antibody (J7E) | WB | |
| TAB-1050CL | Mouse Anti-PMEL Recombinant Antibody (TAB-1050CL) | FC, FuncS | Mouse IgG |
| TAB-1051CL | Mouse Anti-PMEL Recombinant Antibody (TAB-1051CL) | FC | Mouse IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0325MZ | Recombinant Mouse Anti-Human PMEL Antibody (clone IMB46) | IHC | Mouse antibody |
| ZG-0592F | Mouse Anti-PMEL Recombinant Antibody (clone HMB45) | IHC-P | Mouse IgG1 |
| ZG-0353U | Rabbit Anti-PMEL Recombinant Antibody (clone P14-V) | IHC-P | Rabbit IgG |
| VS3-CJ934 | Mouse Anti-PMEL Recombinant Antibody (clone PT1593) | IHC-P | Mouse IgG2b, κ |
| VS3-CJ935 | Mouse Anti-PMEL Recombinant Antibody (clone ABT-PMEL) | IHC-P | Mouse IgG2b, κ |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2761 | Hi-Affi™ Recombinant Rabbit Anti-PMEL Monoclonal Antibody (DS2761AB) | IHC-P | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0046-LSX-S(P) | Mouse Anti-PMEL Recombinant Antibody; scFv Fragment (HPAB-0046-LSX-S(P)) | ELISA, WB, FC | Mouse scFv |
| HPAB-0047-LSX-S(P) | Mouse Anti-PMEL Recombinant Antibody; scFv Fragment (HPAB-0047-LSX-S(P)) | ELISA, WB, FC | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0046-LSX-F(E) | Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (HPAB-0046-LSX-F(E)) | ELISA, WB, FC | Mouse Fab |
| HPAB-0047-LSX-F(E) | Human Anti-PMEL Recombinant Antibody; Fab Fragment (HPAB-0047-LSX-F(E)) | ELISA, WB, FC | Chimeric Fab |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF186 | H-2Db/HPV16 E7 (RAHYNIVTF) MHC Monomer | MHC Multimer | |
| MHC-YF214 | B*15:01/EBV EBNA4 (GQGGSPTAM) MHC Monomer | MHC Multimer | |
| MHC-YF225 | A*02:01/HPV16 E7 (YMLDLQPET) MHC Monomer | MHC Multimer | |
| MHC-YF295 | A*02:01/HPV E7 (YMLDLQPETT) MHC Monomer | MHC Multimer |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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