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CD20 & CD22

Anti-CD20 & CD22 Products

Anti-Human CD22 Recombinant Antibody (TAB-183-F(E)) (TAB-183-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fv - disulfide stabilized
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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Humanized Anti-CD22 Recombinant Antibody (clone Inotuzumab) (TAB-198)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG4, κ
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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Anti-Human CD22 Recombinant Antibody (TAB-176) (TAB-176)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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Mouse Anti-Human CD22 Recombinant Antibody (TAB-003LC)
- Application: FC
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Mouse Anti-CD22 Recombinant Antibody (HPAB-1899LY) (HPAB-1899LY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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Mouse Anti-CD22 Recombinant Antibody (TAB-005LC) (TAB-005LC)
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC, Cyt, Block, Apop, ROS assay, FuncS
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Mouse Anti-CD22 Recombinant Antibody (clone AB008) (HPAB-0709-FY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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Mouse Anti-CD22 Recombinant Antibody (HPAB-1900LY) (HPAB-1900LY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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Human Anti-CD22 Recombinant Antibody (TAB-1717CL) (TAB-1717CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Mouse Anti-CD22 Recombinant Antibody (HPAB-1901LY) (HPAB-1901LY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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Mouse Anti-CD22 Recombinant Antibody (HPAB-1902LY) (HPAB-1902LY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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Human Anti-CD22 Recombinant Antibody (TAB-1718CL) (TAB-1718CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Human Anti-CD22 Recombinant Antibody (TAB-1719CL) (TAB-1719CL)
- Derivation: Human
- Type: Fully human antibody
- Application: ELISA
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Mouse Anti-CD22 Recombinant Antibody (HPAB-1903LY) (HPAB-1903LY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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Anti-Human CD22 Recombinant Antibody (hLL2-Cys) (TAB-0197CL)
- Application: ELISA, In vivo
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Human Anti-CD22 Antibody, mRNA (TAB-198-mRNA) (TAB-198-mRNA)
- Species Reactivity: Human
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Anti-Human CD22 Recombinant Antibody (hLL2) (TAB-0196CL)
- Application: Inhib, Cyt, FC, WB
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Human Anti-CD22 Antibody (clone g5/44), mRNA (FAMAB-0047YC-mRNA)
- Species Reactivity: Human
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Mouse Anti-CD22 Antibody (clone m5/44), mRNA (FAMAB-0046YC-mRNA)
- Species Reactivity: Human
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Human Anti-CD22 Recombinant Antibody (TAB-1716CL) (TAB-1716CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Human Anti-CD22 Recombinant Antibody (TAB-1715CL) (TAB-1715CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Human Anti-CD22 Recombinant Antibody (clone B28) (HPAB-2052-FY)
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC
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Mouse Anti-CD22 Recombinant Antibody (clone 2H1C4) (VS3-XY236)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, FC, ICC
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Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2-Cys) (TAB-0197CL-F(E))
- Application: ELISA, In vivo
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Mouse Anti-CD22 Recombinant Antibody (clone 5LB129) (MOB-0349MZ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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Mouse Anti-CD22 Recombinant Antibody (clone 1A3A11) (VS3-XY235)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, ICC, FC
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Mouse Anti-CD22 Recombinant Antibody (clone m5/44) (FAMAB-0046YC)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, Cyt
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Human Anti-CD22 Recombinant Antibody (clone g5/44) (FAMAB-0047YC)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG4
- Application: ELISA, Cyt
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Human Anti-CD22 Recombinant Antibody (clone ch5/44) (FAMAB-0048YC)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
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Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-001LC-F(E)) (TAB-001LC-F(E))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Anti-Human CD22 Recombinant Antibody Fab Fragment (VM1000) (TAB-002LC-F(E))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, SPR
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1715CL-F(E)) (TAB-1715CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1716CL-F(E)) (TAB-1716CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1717CL-F(E)) (TAB-1717CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1718CL-F(E)) (TAB-1718CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1719CL-F(E)) (TAB-1719CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1720CL-F(E)) (TAB-1720CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1721CL-F(E)) (TAB-1721CL-F(E))
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Human Anti-CD22 Recombinant Antibody Fab Fragment (TAB-1722CL-F(E)) (TAB-1722CL-F(E))
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Afuco™ Anti-CD22 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-176) (AFC-TAB-176)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IF, IP, Neut, FuncS, ELISA, FC
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Afuco™ Anti-CD22 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-198) (AFC-TAB-198)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, FC, IP, FuncS, IF, Neut
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Mouse IgG1, kappa Anti-CD22 Recombinant Antibody (MOB-1248z) (MOB-1248z)
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IF, FC
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Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2) (TAB-0196CL-F(E))
- Application: ELISA, In vivo
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Human Anti-CD22 Recombinant Antibody (TAB-001LC) (TAB-001LC)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Anti-Human CD22 Recombinant Antibody (VM1000) (TAB-002LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: FC, ELISA, SPR, FuncS
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Humanized Anti-CD22 Recombinant Antibody (clone Pinatuzumab) (TAB-899)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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Anti-CD22 immunotoxin RFB4 (IgG)-PE (AGTO-G077E)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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anti-CD22 immunotoxin RFB4 (scFv)-PE (AGTO-L048E)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Anti-CD22 immunotoxin RFB4 (IgG)-DT (AGTO-G077D)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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anti-CD22 immunotoxin RFB4 (scFv)-DT (AGTO-L048D)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Anti-CD22 immunotoxin RFB4 (IgG)-Gel (AGTO-G077G)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Anti-CD22 immunotoxin RFB4 (IgG)-RTA (AGTO-G077R)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Anti-CD22 immunotoxin RFB4 (IgG)-Sap (AGTO-G077S)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Recombinant Anti-Human CD22 Antibody Fab Fragment (MOB-1248z-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, RIA, FuncS
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Recombinant Anti-Human CD22 Antibody scFv Fragment (MOB-1248z-S(P))
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
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Anti-Human CD22 Recombinant Antibody Fab Fragment(Bectumomab) (TAB-047-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab' - G2a - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
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anti-CD22 immunotoxin RFB4 (scFv)-Gel (AGTO-L048G)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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anti-CD22 immunotoxin RFB4 (scFv)-RTA (AGTO-L048R)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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anti-CD22 immunotoxin RFB4 (scFv)-Sap (AGTO-L048S)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Anti-Human CD22 Recombinant Antibody (TAB-004LC)
- Application: FC
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Recombinant Human Anti-CD22 Antibody Fab Fragment (HPAB-0249-FY-F(E))
- Derivation: Chimeric
- Species Reactivity: Human
- Type: Human Fab
- Application: F
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Mouse Anti-CD22 Recombinant Antibody (TAB-1714CL) (TAB-1714CL)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB
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Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1714CL-F(E)) (TAB-1714CL-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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Mouse Anti-CD22 Recombinant Antibody (clone m5/44); Fab Fragment (FAMAB-0046-YC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Cyt
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Human Anti-CD22 Recombinant Antibody (clone B28); Fab Fragment (HPAB-2052-FY-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: FC
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Human Anti-CD22 Recombinant Antibody (clone B28); scFv Fragment (HPAB-2052-FY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
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Anti-CD22 (Pinatuzumab)-MC-VC-PABC-MMAE ADC (ADC-034LCT)
- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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Anti-CD22 (clone 10F4v3)-SMCC-DM1 ADC (ADC-219CL)
- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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Anti-CD22 (Inotuzumab)-hydrazone-Calicheamicin ADC (ADC-036LCT)
- Target: CD22
- Linker: hydrazone
- Drug: Calicheamicin
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Anti-CD22 (clone 10F4v3)-MC-MMAF ADC (ADC-220CL)
- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Anti-CD22 (Inotuzumab)-DIBO-doxorubicin ADC (ADC-037LCT)
- Target: CD22
- Linker: DIBO (dibenzylcyclooctynol)
- Drug: doxorubicin
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Anti-CD22 (clone 10F4v2)-MC-MMAF ADC (ADC-218CL)
- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Recombinant Anti-CD20 × Anti-CD22 Bispecific Antibody (Tandem Diabody) (TAND-L039)
- Targets: CD20 & CD22
- Type: Tandem Diabody
- Application: FuncS, Promising therapeutic agent
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Anti-CD22-MC-MMAF ADC (ADC-032LCT)
- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Anti-CD22-CL2E-SN-38 ADC (ADC-031LCT)
- Target: CD22
- Linker: CL2E
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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Recombinant Anti-Human CD22 Antibody (Fab glycosylation) (Gly-001LC)
- Host Species: Mouse
- Specificity: Human
- Type: Mouse antibody
- Classification: Fab glycosylation
- Glycosylation site: FR1 of VK
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Anti-CD22-MCC-DM1 ADC (ADC-033LCT)
- Target: CD22
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB) (MOR-0545)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IP, WB
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Anti-CD22 (clone 10F4v3)-BMPEO-DM1 ADC (ADC-211CL)
- Target: CD22
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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Anti-CD22 (clone 10F4v3)-MC-MMAF ADC (ADC-212CL)
- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Anti-CD22 (clone 10F4v3)-MC-vc-PAB-MMAE ADC (ADC-213CL)
- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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Anti-CD22 (clone 5E8)-SMCC-DM1 ADC (ADC-214CL)
- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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Anti-CD22 (clone 7A2)-SMCC-DM1 ADC (ADC-215CL)
- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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Anti-CD22 (clone 10F4v1)-SMCC-DM1 ADC (ADC-216CL)
- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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Anti-CD22 (clone 10F4v2)-SMCC-DM1 ADC (ADC-217CL)
- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare

Recombinant Anti-CD20 × Anti-CD22 Bispecific Antibody (CrossMab) (CROSS-L023)
- Targets: CD20 & CD22
- Type: CrossMab
- Application: FuncS, Promising therapeutic agent
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Anti-CD22 (clone hLL2)-SN-38 ADC (ADC-124CL)
- Target: CD22
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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Anti-CD22 (RFB4)-mcc-DM1 ADC (ADC-028LCT)
- Target: CD22
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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Anti-CD22 (10F4)-AcBut-Calicheamicin ADC (ADC-029LCT)
- Target: CD22
- Linker: AcBut
- Drug: Calicheamicin
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Anti-CD22-CL2A-SN-38 ADC (ADC-030LCT)
- Target: CD22
- Linker: CL2A
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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Anti-CD22 (clone hu10F4)-MCC-DM1 ADC (ADC-027LZY)
- Target: CD22
- Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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Anti-CD22-mc-vc-PABc-MMAE ADC (ADC-033LZY)
- Target: CD22
- Linker: mc-VC-PABc(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
Compare

Anti-CD22-mc-vc-PABc-NMS249 ADC (ADC-097LZY)
- Target: CD22
- Linker: mc-VC-PABc (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: NMS249
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Anti-CD22 (clone 10F4v3)-MCC-DM1 ADC (ADC-194LZY)
- Target: CD22
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Compare

Anti-CD22 (clone 10F4v3)-mc-vc-PABC-MMAE ADC (ADC-195LZY)
- Target: CD22
- Linker: mc-VC-PABC(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
Compare

Anti-CD22 (clone G5/44)-AcBut-CalichDMH ADC (ADC-003LZY)
- Target: CD22
- Linker: AcBut (4-(4-acetylphenoxy)butanoic acid)
- Drug: CalichDMH
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Anti-CD22-AcBut-CalichDMH ADC (ADC-006LZY)
- Target: CD22
- Linker: AcBut (4-(4-acetylphenoxy)butanoic acid)
- Drug: CalichDMH
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Anti-CD22 (clone HB22.7)-saporin ADC (ADC-154LZY)
- Target: CD22
- Drug: saporin
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Anti-CD22 (Inotuzumab)-calicheamicin ADC (CMC-544/inotuzumab ozogamicin) (ADC-L024)
- Target: CD22
- Linker: acetyl butyrate linker
- Drug: calicheamicin
Compare

Anti-CD22 (CR011)-vc-MMAE ADC (RG7593) (ADC-L028)
- Target: CD22
- Linker: vc (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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For Research Use Only. Not For Clinical Use.

Background

CD20 is a cell surface protein expressed on B cells. It is a common target for monoclonal antibody therapy in B-cell lymphomas and autoimmune diseases.

CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include refractory hematologic cancer and colon lymphoma. Among its related pathways are Immune System and Downstream signaling events of B Cell Receptor (BCR). GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is VCAM1.