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IL2RA & CD3
Engineered Antibody Products
Antibody-like Scaffold Protein Products
Glyco-Engineering Antibody Products
Antibody Magnetic Beads
Hexamer Antibody Products
Cancer Stem Cell Biomarker Specific Antibody Products
AbPlus
Recombinant Antibody Products
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Anti-IL2RA & CD3 Recombinant Antibody Products
- AbPlus™ Anti-IL2RA Magnetic Beads (2R12) (VS-0424-XY150)
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- Target: IL2RA
- Target Species: Human
- Application: IP, Protein Purification
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- IL2-RTA immunotoxin (AGTO-L078R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- IL2-DT immunotoxin (AGTO-L078D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- IL2-PE immunotoxin (AGTO-L078E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-IL2RA immunotoxin RFT5 (IgG)-RTA (AGTO-L028R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-IL2RA immunotoxin RFT5 (IgG)-DT (AGTO-L028D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-IL2RA immunotoxin RFT5 (IgG)-PE (AGTO-L028E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-IL2RA immunotoxin RFT5 (scFv)-RTA (AGTO-L027R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-IL2RA immunotoxin RFT5 (scFv)-DT (AGTO-L027D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-IL2RA immunotoxin RFT5 (scFv)-PE (AGTO-L027E)
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- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.