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    Human Anti-CD74 Recombinant Antibody (clone Milatuzumab) (CAT#: VS-0723-WK3)

    This product is a humanized IgG1 antibody that recognizes human CD74, which is associated with undifferentiated pleomorphic sarcoma and mantle cell lymphoma. Milatuzumab is recommended for flow cytometry at a concentration of 15 μg/mL.

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    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/if_selected.jpg
    Figure 2 IHC staining of human spleen
    Figure 2 IHC staining of human spleen
    (Immunohistochemical staining of human spleen shows strong granular cytoplasmic positivity.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10592/ihc_selected.jpg
    Figure 3 IHC staining of human tonsil
    Figure 3 IHC staining of human tonsil
    (Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79994/170659_A_6_8_selected.jpg
    Figure 4 IF staining of human cell line U-251 MG
    Figure 4 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/203_F11_1_blue_red_green.jpg
    Normal Tissue
    Figure 5 Colon
    Figure 5 Colon
    (Mucosal lymphoid cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_7_3.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_5.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_8.jpg
    Figure 8 Tonsil
    Figure 8 Tonsil
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_6_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)
    Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000019582-CD74

    Specifications

    • Immunogen
    • Recombinant human CD74 protein
    • Host Species
    • Human
    • Derivation
    • Humanized
    • Type
    • Human IgG1
    • Specificity
    • Human CD74
    • Species Reactivity
    • Human
    • Clone
    • Milatuzumab
    • Applications
    • FC
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Purity
    • >95%
    • Format
    • Lyophilized
    • Buffer
    • Lyophilized from sterile PBS (pH 7.4) with 5%-8% trehalose.
    • Preservative
    • No Preservative
    • Storage
    • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Flow Cytometry: 1/100

    Target

    • Alternative Names
    • DHLAG
    • Long Name
    • CD74 Molecule

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CD74"

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    CAT Product Name Application Type
    TAB-0004CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0004CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
    TAB-0005CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0005CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
    TAB-0006CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0006CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
    TAB-0007CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0007CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
    TAB-0011CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0011CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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