This product is a recombinant mouse antibody that recognizes DSG3. The antibody was purified by affinity chromatography. It can be used in ELISA, IF.
Figure 1 Cryosections of human skin were stained with biotinylated human mAbs isolated from PV patients.
The cutaneous basement membrane zone is marked by a dotted line. Scale bars: 100 μm.
Di Zenzo, G., Di Lullo, G., Corti, D., Calabresi, V., Sinistro, A., Vanzetta, F., ... & Amagai, M. (2012). Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface. The Journal of clinical investigation, 122(10), 3781-3790.
Figure 2 Binding of the indicated antibodies to DSG3-coated plates in the presence or absence of EDTA as assessed by ELISA.
Data are representative of 2 separate experiments (mean ± SEM).
Di Zenzo, G., Di Lullo, G., Corti, D., Calabresi, V., Sinistro, A., Vanzetta, F., ... & Amagai, M. (2012). Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface. The Journal of clinical investigation, 122(10), 3781-3790.
Figure 3 Intraepidermal suprabasal blistering and acantholysis induced by injection into newborn mice of the indicated antibodies coadministered with ETA.
Data are representative of results obtained from groups of 5 mice. Original magnification, ×200.
Di Zenzo, G., Di Lullo, G., Corti, D., Calabresi, V., Sinistro, A., Vanzetta, F., ... & Amagai, M. (2012). Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface. The Journal of clinical investigation, 122(10), 3781-3790.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-172 | Human Anti-DSG3 Recombinant Antibody (clone PVA3) | ELISA | Human IgG |
FAMAB-0203-CN | Human Anti-DSG3 Recombinant Antibody (clone (D3)1b/3a) | ELISA, IF, IB | Human IgG |
FAMAB-0204-CN | Human Anti-DSG3 Recombinant Antibody (clone (D3)3c/9) | ELISA, IF, IB | Human IgG |
FAMAB-0205-CN | Human Anti-DSG3 Recombinant Antibody (clone (D3)3a/9) | ELISA, IF, IB | Human IgG |
FAMAB-1111CQ | Human Anti-DSG3 Recombinant Antibody (clone PVA224) | IF, ELISA, IHC | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-258MZ | Anti-Human DSG3 Recombinant Antibody (DF151) | IHC, FC | |
TAB-259MZ | Anti-Human DSG3 Recombinant Antibody (DF364) | IHC, FC | |
TAB-260MZ | Anti-Human DSG3 Recombinant Antibody (DF366) | IHC, FC | |
TAB-258MZ-S(P) | Anti-Human DSG3 Recombinant Antibody scFv Fragment (DF151) | IHC, FC | |
TAB-259MZ-S(P) | Anti-Human DSG3 Recombinant Antibody scFv Fragment (DF364) | IHC, FC |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1055 | Hi-Affi™ Rabbit Anti-DSG3 Recombinant Antibody (clone DS1055AB) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0203-CN-S(P) | Human Anti-DSG3 Recombinant Antibody (clone (D3)1b/3a); scFv Fragment | ELISA, IF, IB | Human scFv |
FAMAB-0204-CN-S(P) | Human Anti-DSG3 Recombinant Antibody (clone (D3);3c/9); scFv Fragment | ELISA, IF, IB | Human scFv |
FAMAB-0205-CN-S(P) | Human Anti-DSG3 Recombinant Antibody (clone (D3)3a/9); scFv Fragment | ELISA, IF, IB | Human scFv |
FAMAB-0152JF-S(P) | Human Anti-DSG3 Recombinant Antibody (clone PVMAB786); scFv Fragment | IF, WB, ELISA, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0203-CN-F(E) | Human Anti-DSG3 Recombinant Antibody (clone (D3)1b/3a); Fab Fragment | ELISA, IF, IB | Human Fab |
FAMAB-0204-CN-F(E) | Human Anti-DSG3 Recombinant Antibody (clone (D3)3c/9); Fab Fragment | ELISA, IF, IB | Human Fab |
FAMAB-0205-CN-F(E) | Human Anti-DSG3 Recombinant Antibody (clone (D3)3a/9); Fab Fragment | ELISA, IF, IB | Human Fab |
FAMAB-0152JF-F(E) | Human Anti-DSG3 Recombinant Antibody (clone PVMAB786); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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