Recombinant Human Anti-GPC3 Soluble TCR (P1-1) (KIH) (CAT#: VS-0622-YF5555)
Human TCR (P1-1) recognizes GPC3 peptide (FIDKKVLKV) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6316/1404_H7_2_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6316/1404_H7_2_selected.jpg
Figure 2 RNA cell line category: Group enriched (HAP1, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147257-GPC3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147257-GPC3
Specifications
- Host Species
- Human
- Target
- GPC3
- Species Reactivity
- Human
- Epitope
- FIDKKVLKV
- MHC
- HLA-A2
- Clone
- P1-1
- Type
- Soluble TCR (KIH)
- Related Disease
- Hepatocellular carcinoma
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- GPC3; glypican 3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; glypican-3; secreted glypican-3; glypican proteoglycan 3
- Gene ID
- 2719
- UniProt ID
- P51654
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1563z | Mouse Anti-GPC3 Recombinant Antibody (clone 29F5) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MOB-0406ZL | Mouse Anti-GPC3 Recombinant Antibody (clone YC080) | WB, IHC, IF, FC | |
| MOB-0407ZL | Human Anti-Gpc3 Recombinant Single Domain Antibody (clone YC087) | ELISA, WB, IHC, FuncS | Human VHH |
| HPAB-0553-CN | Human Anti-GPC3 Recombinant Antibody (clone GES1) | ELISA, FC, IF, IP | Chimeric (chicken/human) IgG1 |
| HPAB-0554-CN | Human Anti-GPC3 Recombinant Antibody (clone huG5S1) | ELISA, FC, IF, IP | Humanized IgG1 |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-069 | Recombinant Anti-Mouse Gpc3 VHH Single Domain Antibody | WB, ELISA, IHC, FuncS | Llama VHH |
| TAB-416CQ | Anti-Human GPC3 Therapeutic Single Domain Antibody (HN3) | IP, IHC, FuncS, WB, ELISA, Inhib | Single domain antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H14 | Anti-Human GPC3 Recombinant Antibody (Codrituzumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 - kappa |
| TAB-160CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-160CT-F(E)) | FC | Humanized Fab |
| TAB-161CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-161CT-F(E)) | FC | Humanized Fab |
| TAB-162CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-162CT-F(E)) | FC | Humanized Fab |
| TAB-163CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-163CT-F(E)) | FC | Humanized Fab |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G035E | Anti-Gpc3 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-157CT | Human Anti-GPC3 Recombinant Antibody (TAB-157CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
| TAB-158CT | Human Anti-GPC3 Recombinant Antibody (TAB-158CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
| TAB-157CT-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-157CT-S(P)) | ELISA, FC, IHC, WB | Mouse scFv |
| TAB-157CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-157CT-F(E)) | ELISA, FC, IHC, WB | Chimeric (mouse/human) Fab |
| TAB-158CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-158CT-F(E)) | ELISA, FC, IHC, WB | Chimeric (mouse/human) Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-167CT | Human Anti-GPC3 Recombinant Antibody (TAB-167CT) | ELISA, FC | Human IgG |
| TAB-168CT | Human Anti-GPC3 Recombinant Antibody (TAB-168CT) | ELISA, FC | Human IgG |
| TAB-152CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-152CT-S(P)) | IB, Funcs, ELISA, FC, IF, WB | Human scFv |
| TAB-167CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-167CT-S(P)) | ELISA, FC | Human scFv |
| TAB-168CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-168CT-S(P)) | ELISA, FC | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-263CQ | Anti-Human GPC3 Recombinant Antibody (YP7) | ELISA, Inhib, IHC | |
| TAB-263CQ-S(P) | Anti-Human GPC3 Recombinant Antibody scFv Fragment (YP7) | ELISA, WB, FC, IHC | |
| TAB-263CQ-F(E) | Anti-Human GPC3 Recombinant Antibody Fab Fragment (YP7) | ELISA, WB, FC, IHC |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1486 | Hi-Affi™ Rabbit Anti-GPC3 Recombinant Antibody (clone DS1486AB) | IHC-P | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0553-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone GES1); Fab Fragment | ELISA, FC, IF, IP | Human Fab |
| HPAB-0554-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone huG5S1); Fab Fragment | ELISA, FC, IF, IP | Humanized Fab |
| HPAB-0556-CN-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0556-CN-F(E)) | ELISA, WB | Human Fab |
| HPAB-0558-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0558-CN-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0560-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0560-CN-F(E)) | ELISA, WB | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1697LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone G5S8); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
| HPAB-1698LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone GES2); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
| HPAB-1699LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone GES6); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
| HPAB-1700LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone GES8); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
| HPAB-0449-FY-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-0449-FY-S(P)) | ELISA | Mouse scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H14 | Afuco™ Anti-GPC3 ADCC Recombinant Antibody (Codrituzumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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