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FcγRI & CD33
Engineered Antibody Products
Glyco-Engineering Antibody Products
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Cancer Stem Cell Biomarker Specific Antibody Products
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Recombinant Antibody Products
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Anti-FcγRI & CD33 Recombinant Antibody Products
- Anti-CD33 (clone h2H12) ADC (ADC-093CL)
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- Target: CD33
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- Anti-CD33 (clone hP67.6)-calicheamicin ADC (ADC-143CL)
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- Target: CD33
- Drug: calicheamicin
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- Anti-CD33 (clone h2H12d) ADC (ADC-144CL)
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- Target: CD33
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- Anti-CD33 (clone m2H12)-mc-MMAF ADC (ADC-145CL)
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- Target: CD33
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Anti-CD33 (clone h2H12)-mc-MMAF ADC (ADC-146CL)
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- Target: CD33
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Anti-CD33 (HuM195)-AcBut-Calicheamicin ADC (ADC-056LCT)
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- Target: CD33
- Linker: AcBut
- Drug: Calicheamicin
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Asn73 in FR of VH
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- Anti-CD33 (h2H12)-vc-PABC-MMAE ADC (ADC-063LCT)
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- Target: CD33
- Linker: VC-PABC (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-CD33 (clone hP67.6)-AcBut-Calicheamicin ADC (ADC-007LZY)
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- Target: CD33
- Linker: AcBut (4-(4-acetylphenoxy)butanoic acid)
- Drug: Calicheamicin
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- Anti-CD33 (clone huMy9-6)-SPDB-DM4 ADC (ADC-023LZY)
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- Target: CD33
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-CD33 (clone h2H12ec)-mc-vc-PBD ADC (ADC-044LZY)
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- Target: CD33
- Linker: mc-VC (maleimidocaproyl-valine-alanine)
- Drug: pyrrolobenzodiazepine (PBD) dimers
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- Target: CD33
- Linker: mc-vc (maleimidocaproyl-valine-alanine)
- Drug: pyrrolobenzodiazepine (PBD) dimers SGD-1882
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- Anti-CD33mAb-DOTA-G3FC ADC (ADC-057LCT)
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- Target: CD33
- Linker: DOTA-G3FC
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- Anti-CD33mAb-DOTA-NCS ADC (ADC-058LCT)
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- Target: CD33
- Linker: DOTA-NCS
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- Anti-CD33mAb-DOTA-SH ADC (ADC-059LCT)
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- Target: CD33
- Linker: DOTA-SH
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- Anti-CD33 (Gemtuzumab)-hydrazone-Calicheamicin ADC (ADC-060LCT)
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- Target: CD33
- Linker: hydrazone
- Drug: Calicheamicin
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- Anti-CD33 (HuM195)-SPDB-DM4 ADC (ADC-061LCT)
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- Target: CD33
- Linker: SPDB
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-CD33 (h2H12)-mc-vc-PBD ADC (ADC-062LCT)
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- Target: CD33
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: pyrrolobenzodiazepine (PBD) dimers
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
CD33 (CD33 Molecule) is a Protein Coding gene. Diseases associated with CD33 include Gallbladder Lymphoma and Extracutaneous Mastocytoma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor activity and carbohydrate binding. An important paralog of this gene is SIGLEC6.
