Rabbit Anti-MS4A1 Recombinant Antibody (clone R04-6H2)
CAT#: VS3-XY3434
This antibody is a recombinant rabbit antibody against MS4A1 (Membrane spanning 4-domains A1), which plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. It specifically reacts with human MS4A1. It has been reported for use in Western Blot, Immunohistochemistry-Paraffin and Flow cytometry.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line REH
Immunofluorescent staining of human cell line REH shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/1778_G3_5_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/201_H5_1_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/202_H5_1_red_green.jpg
Normal Tissue
Figure 4 Colon
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_3.jpg
Normal Tissue
Figure 5 Bone marrow
Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_B_4_4.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000156738-MS4A1
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MS4A1
- Species Reactivity
- Human
- Clone
- R04-6H2
- Applications
- WB, IHC-P, FC
- Related Disease
- Immunodeficiency, Common Variable, 5; Common Variable Immunodeficiency
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
FC: 1/50-1/100
Target
- Alternative Names
- B1; S7; Bp35; CD20; FMC7; CVID5; LEU-16
- Gene ID
- 931
- UniProt ID
- P11836
- Long Name
- Membrane spanning 4-domains A1
- Sequence Similarities
- Belongs to the MS4A family.
- Cellular Localization
- Cell membrane, Membrane
- Post Translation Modifications
- Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate.
- Protein Refseq
- NP_068769.2; NP_690605.1
- Function
- B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes.
Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-028 | Anti-Human CD20 Recombinant Antibody (TAB-028) | FC, IP, ELISA, Neut, FuncS, IF, IHC | IgG1 - kappa |
| TAB-1648CL-S(P) | Anti-MS4A1 Recombinant Antibody scFv Fragment (MEDI-552) | Inhib | |
| TAB-1654CL-S(P) | Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1654CL-S(P)) | FC, Apop | Human scFv |
| TAB-1655CL-S(P) | Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1655CL-S(P)) | ELISA | Human scFv |
| TAB-1674CL-S(P) | Human Anti-MS4A1 Recombinant Antibody scFv Fragment (TAB-1674CL-S(P)) | Cyt, ELISA, FuncS, Inhib |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-207 | Anti-Human CD20 Recombinant Antibody | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 - kappa |
| TAB-1670CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1670CL-F(E)) | CDC | Chimeric (mouse/human) Fab |
| TAB-1671CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1671CL-F(E)) | CDC | Chimeric (mouse/human) Fab |
| TAB-1675CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1675CL-F(E)) | ELISA, WB | Chimeric (mouse/human) Fab |
| TAB-1692CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (Zytux) | ELISA, WB | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1635CL | Anti-Human MS4A1 Recombinant Antibody (BVX20) | Inhib | Humanized antibody |
| TAB-1636CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1636CL) | ADCC, CDC | Humanized IgG |
| TAB-1637CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1637CL) | ADCC, CDC | Humanized IgG |
| TAB-1638CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) | ADCC, CDC | Humanized IgG |
| TAB-1639CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) | ADCC, CDC, Apop | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-059LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
| Gly-063LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
| Gly-097LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
| Gly-115LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| Gly-138LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-063LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
| Gly-134LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
| Gly-135LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
| Gly-136LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
| Gly-158LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-142LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-155LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-171LC | Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0279MZ | Mouse Anti-MS4A1 Recombinant Antibody (clone M27 (1, 4).) | IHC | Mouse IgG2a |
| HPAB-1693LY | Mouse Anti-MS4A1 Recombinant Antibody (HPAB-1693LY) | Neut, FC, IHC-Fr, IHC-P, IP | Mouse IgG |
| HPAB-1694LY | Human Anti-MS4A1 Recombinant Antibody (HPAB-1694LY) | Inhib | Humanized IgG |
| HPAB-1321-FY | Human Anti-MS4A1 Recombinant Antibody (HPAB-1321-FY) | FC, ELISA | Human IgG |
| HPAB-1322-FY | Human Anti-MS4A1 Recombinant Antibody (HPAB-1322-FY) | FC, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC066 | PE-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
| MHC-LC067 | APC-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
| MHC-LC068 | BV421-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
| MHC-LC4347 | PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1751CQ | Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) | Neut, FuncS | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2295 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone DS2295AB) | IHC-Fr, IHC-P | Rabbit IgG |
| MOR-4024 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone SI88DS) | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0683-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone Rmut8); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-0684-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone Rmut5); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-0742-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-0742-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0743-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-0743-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0744-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-0744-CN-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0704-YC | Camelid Anti-MS4A1 Recombinant Antibody (HPAB-M0704-YC) | ELISA, FuncS | Camelid VHH |
| HPAB-M0705-YC | Camelid Anti-MS4A1 Recombinant Antibody (HPAB-M0705-YC) | ELISA | Camelid VHH |
| HPAB-M0706-YC | Camelid Anti-MS4A1 Recombinant Antibody (HPAB-M0706-YC) | ELISA | Camelid VHH |
| HPAB-M0707-YC | Camelid Anti-MS4A1 Recombinant Antibody (HPAB-M0707-YC) | ELISA | Camelid VHH |
| HPAB-M0708-YC | Camelid Anti-MS4A1 Recombinant Antibody (HPAB-M0708-YC) | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-772 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-772) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| AFC-TAB-016 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-016) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-028 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-028) | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-207 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-207) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| AFC-TAB-771 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-771) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0614-WJ-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (HPAB-0614-WJ-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0615-WJ-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (HPAB-0615-WJ-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0616-WJ-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (HPAB-0616-WJ-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-1321-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1321-FY-F(E)) | FC, ELISA | Human Fab |
| HPAB-1322-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1322-FY-F(E)) | FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY188 | AbPlus™ Anti-MS4A1 Magnetic Beads (VS-0424-XY188) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC138 | Human Anti-MS4A1 Recombinant Antibody Hexamer (VS-0924-YC138), CDC Enhanced | FC, CDC, IP | Antibody hexamer |
| VS-0924-YC139 | Mouse Anti-MS4A1 Recombinant Antibody Hexamer (VS-0924-YC139), CDC Enhanced | FC, Activ, Agonist, IF, WB, Cyt, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY85 | Mouse Anti-NHP MS4A1 Recombinant Antibody (VS-1024-XY85) | FC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY30 | Human Anti-MS4A1 (clone RW005) scFv-Fc Chimera | FuncS | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY168 | CytoStream™ Rat Anti-MS4A1 Recombinant Antibody (clone GOT214A) | FC | Rat IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC513 | Recombinant Anti-MS4A1 Vesicular Antibody, EV Displayed (VS-0425-YC513) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4510 | Anti-MS4A1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4511 | Anti-Mouse MS4A1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC129 | Recombinant Anti-MS4A1 (Bin I x Bin II) Biparatopic Antibody, Tandem scFv | ELISA, FC | Tandem scFv |
| VS-0525-YC222 | Recombinant Anti-MS4A1 Biparatopic Antibody, Tandem scFv | ELISA, IF, WB | Tandem scFv |
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