Human Anti-HCV E2 Recombinant Antibody (clone 9e1) (CAT#: FAMAB-0358JF)

Recombinant monoclonal antibody specially binds to HCV E2 envelope protein. This human anti-core protein antibody (9e1) can be widely used in the detection of patients with HCV infection.


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ELISA

Figure 1 E2-specific human mAbs.

Figure 1 E2-specific human mAbs.

Antibody competition study. Numbers indicate percentage of residual binding signals of biotinylated human mAbs in the presence of blocking mAbs, and the extent of competition is highlighted by warmth of color.

Law, M., Maruyama, T., Lewis, J., Giang, E., Tarr, A. W., Stamataki, Z., ... & Ball, J. K. (2008). Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nature medicine, 14(1), 25-27.

WB

Figure 2 WB analysis proteins in the lysate of HEK 293T cells cotransfected with different plasmids.

Figure 2 WB analysis proteins in the lysate of HEK 293T cells cotransfected with different plasmids.

The immune complexes were analyzed by SDS-10% PAGE under reducing conditions.

Owsianka, A., Tarr, A. W., Juttla, V. S., Lavillette, D., Bartosch, B., Cosset, F. L., ... & Patel, A. H. (2005). Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein. Journal of virology, 79(17), 11095-11104.

Neut

Figure 3 Neutralization of HCVpp infection by anti-E2 antibodies.

Figure 3 Neutralization of HCVpp infection by anti-E2 antibodies.

Neutralization of HCVpp derived from E1E2 of three different genotype 1a subtypes.

Owsianka, A., Tarr, A. W., Juttla, V. S., Lavillette, D., Bartosch, B., Cosset, F. L., ... & Patel, A. H. (2005). Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein. Journal of virology, 79(17), 11095-11104.


Specifications

  • Host Species
  • Human
  • Derivation
  • Human phage display scFv library
  • Type
  • Human IgG
  • Specificity
  • HCV E2 envelope protein
  • Species Reactivity
  • HCV
  • Clone
  • 9e1
  • Applications
  • WB, ELISA, Neut
  • Related Disease
  • HCV infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HCV E2 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Neutralization.

Target

  • Alternative Names
  • Hepatitis C virus; HCV; HCV E2; Hepatitis C virus E2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 9e1"

See other products for "HCV E2 protein"

Mouse Antibody

CAT Product Name Application Type
MRO-1191LC Anti-HCV E2 Recombinant Antibody (A10F2) ELISA, Inhib Mouse Antibody
MRO-1192LC Anti-HCV E2 Recombinant Antibody (H6D3) ELISA, Inhib, WB Mouse Antibody
MRO-1193LC Anti-HCV E2 Recombinant Antibody (E3D8) ELISA, Inhib, WB Mouse Antibody
MRO-1194LC Anti-HCV E2 Recombinant Antibody (A7A6H9) ELISA, Inhib Mouse Antibody
MRO-1195LC Anti-HCV E2 Recombinant Antibody (G9E1) ELISA, Inhib Mouse Antibody

MHC Tetramer for Virology

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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