What is the host species and target for this antibody?

This is a recombinant Human IgG antibody that specifically recognizes MSLN (Mesothelin), a protein often overexpressed in mesothelioma and ovarian cancer.

Is this antibody suitable for Flow Cytometry?

Yes, this antibody is purified by affinity chromatography (>95% purity) and has been validated for use in Flow Cytometry (FC) and ELISA.

Human Anti-MSLN Recombinant Antibody (HPAB-1341-FY)

CAT#: HPAB-1341-FY

This product is a recombinant human antibody that recognizes MSLN. The antibody was purified by affinity chromatography. It can be used for ELISA, FC and other applications.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HeLa

Immunofluorescent staining of human cell line HeLa shows localization to vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17172/1276_A4_4_selected.jpg

Normal Tissue Figure 2 Fallopian tube

Ciliated cells (cilia axoneme)
Staining:

High

Intensity: Strong

Ciliated cells (tip of cilia)
Staining:

High

Intensity: Strong

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2216/6076_A_7_7.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, EFO-21, HeLa, hTCEpi, OE19)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102854-MSLN

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Specifications

Host Species
Human

Type
Human IgG

Specificity
Human MSLN

Species Reactivity
Human, Mouse

Applications
ELISA, FC

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Mesothelin; Pre-Pro-Megakaryocyte-Potentiating Factor; CAK1 Antigen; MPF; Soluble MPF Mesothelin Related Protein; Megakaryocyte Potentiating Factor; SMRP

Gene ID
10232

UniProt ID
Q13421

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Breast cancer biomarkers at key points during disease progression

Reliable MSLN Detection

This recombinant human antibody against MSLN works reliably in our ELISA and Flow Cytometry assays. It specifically recognizes human Mesothelin, and we have observed consistent staining on ovarian cancer cell lines. The affinity purification yields a clean product.

High Purity Reagent

We appreciate the high purity (>95%) of this antibody. It has been validated for multiple applications, which simplifies our workflow. It is a robust tool for studying MSLN overexpression in various tumor models without background issues.

Q&As

What is the host species and target for this antibody?

A: This is a recombinant Human IgG antibody that specifically recognizes MSLN (Mesothelin), a protein often overexpressed in mesothelioma and ovarian cancer.
Is this antibody suitable for Flow Cytometry?

A: Yes, this antibody is purified by affinity chromatography (>95% purity) and has been validated for use in Flow Cytometry (FC) and ELISA.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-1341-FY.pdf

MSDS

MSDS - HPAB-1341-FY.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

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