Human Anti-MSTN Recombinant Antibody (HPAB-AP390-YC)

Name: Human Anti-MSTN Recombinant Antibody (HPAB-AP390-YC)
SKU: HPAB-AP390-YC
Rating: 5 (1 reviews)

CAT#: HPAB-AP390-YC

This product is a recombinant humanized version of the OGD1.0.0 antibody that recognizes MSTN. The CDR2 amino acid sequence from the humanized VH0 and VL0 regions were compared to the CDR2 sequence from the human germline VH region DP-47 and VL region DPK-9, respectively. All residues in the VH0 and VL0 CDR2 sequences differing from the human sequence were changed to human. The new VH and VL regions were designated VH2 and VL2, respectively. OGD1.0.2 antibody was produced using VH0 and VL2 and did not result in loss of antigen binding.

Gene Expression

Normal Tissue Figure 1 IHC staining of human skeletal muscle

Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg

RNA Expression Figure 2 RNA cell line category: Group enriched (LHCN-M2, RH-30)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN

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Specifications

Host Species
Human

Derivation
Humanized (mouse/human)

Type
Humanized IgG

Specificity
Human MSTN

Species Reactivity
Human

Applications
ELISA, Neut

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
See the COA

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Myostatin; GDF8; Growth Differentiation Factor 8; Growth/Differentiation Factor 8; MSLHP; GDF-8

Gene ID
2660

UniProt ID
O14793

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-AP390-YC.pdf

MSDS

MSDS - HPAB-AP390-YC.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
TAB-451MZ-S(P)	Human Anti-MSTN Recombinant Antibody; scFv Fragment (TAB-451MZ-S(P))	ELISA	Humanized scFv
TAB-451MZ-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-451MZ-F(E))	ELISA	Humanized Fab
TAB-457MZ-F(E)	Anti-Human MSTN Recombinant Antibody Fab Fragment (H0L0)	ELISA	Humanized antibody
TAB-458MZ-F(E)	Anti-Human MSTN Recombinant Antibody Fab Fragment (H1L2)	ELISA	Humanized antibody
TAB-459MZ-F(E)	Anti-Human MSTN Recombinant Antibody Fab Fragment (H2L2)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
TAB-452MZ-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-452MZ-F(E))	ELISA	Human Fab
TAB-453MZ-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-453MZ-F(E))	ELISA	Human Fab
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TAB-460MZ-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-460MZ-F(E))	ELISA	Human Fab
TAB-461MZ-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-461MZ-F(E))	ELISA	Human Fab

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HPAB-0025-FY-S(P)	Human Anti-MSTN Recombinant Antibody; scFv Fragment (HPAB-0025-FY-S(P))	FC	Human scFv
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HPAB-3145LY-S(P)	Human Anti-MSTN Recombinant Antibody; scFv Fragment (HPAB-3145LY-S(P))	ELISA, FC	Human scFv
HPAB-3146LY-S(P)	Human Anti-MSTN Recombinant Antibody; scFv Fragment (HPAB-3146LY-S(P))	ELISA, FC	Human scFv

CAT	Product Name	Application	Type
HPAB-AP389-YC-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (HPAB-AP389-YC-F(E))	ELISA, Neut	Humanized Fab
HPAB-AP390-YC-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (HPAB-AP390-YC-F(E))	ELISA, Neut	Humanized Fab
HPAB-AP391-YC-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (HPAB-AP391-YC-F(E))	ELISA, Neut	Humanized Fab
HPAB-AP392-YC-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (HPAB-AP392-YC-F(E))	ELISA, Neut	Humanized Fab
HPAB-AP393-YC-F(E)	Human Anti-MSTN Recombinant Antibody; Fab Fragment (HPAB-AP393-YC-F(E))	ELISA, Neut	Humanized Fab

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CAT	Product Name	Application	Type
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