Rabbit Anti-NGF Recombinant Antibody (VS3-CJ237) (CAT#: VS3-CJ237)
This product is a rabbit antibody that recognizes NGF.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134259-NGF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134259-NGF
Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat and Zebrafish NGF
- Species Reactivity
- Human, Mouse, Rat, Zebrafish
- Applications
- WB, ICC, IF, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry.
Target
- Alternative Names
- NGFB; HSAN5; Beta-NGF
- Gene ID
- 4803
- UniProt ID
- P01138
- Sequence Similarities
- Belongs to the NGF-beta family.
- Cellular Localization
- Endosome, Secreted
- Protein Refseq
- NP_002497.2
- Function
- Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems (PubMed:14976160, PubMed:20978020).
Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (PubMed:20978020) (Probable). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (By similarity).
Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (By similarity).
Recommended Products
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Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-111 | Anti-Human NGF Recombinant Antibody (TAB-111) | ELISA, FuncS, Inhib | IgG2 |
| TAB-686CL | Anti-Human NGF Therapeutical Antibody (TAB-686CL) | FuncS | Antibody |
| TAB-501MZ | Anti-Human NGF Recombinant Antibody (TAB-501MZ) | ELISA | Humanized antibody |
| TAB-501MZ-S(P) | Anti-Human NGF Recombinant Antibody scFv Fragment (TAB-501MZ-S(P)) | ELISA, IRMA, RIA, IHC | Humanized antibody |
| TAB-501MZ-F(E) | Anti-Human NGF Recombinant Antibody Fab Fragment (TAB-501MZ-F(E)) | ELISA, IRMA, RIA, IHC | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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