Rabbit Anti-NGF Recombinant Antibody (VS3-CJ237)
CAT#: VS3-CJ237
This product is a rabbit antibody that recognizes NGF.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134259-NGF
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Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat and Zebrafish NGF
- Species Reactivity
- Human, Mouse, Rat, Zebrafish
- Applications
- WB, ICC, IF, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry.
Target
- Alternative Names
- NGFB; HSAN5; Beta-NGF
- Gene ID
- 4803
- UniProt ID
- P01138
- Sequence Similarities
- Belongs to the NGF-beta family.
- Cellular Localization
- Endosome, Secreted
- Protein Refseq
- NP_002497.2
- Function
- Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems (PubMed:14976160, PubMed:20978020).
Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (PubMed:20978020) (Probable). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (By similarity).
Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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| TAB-501MZ-S(P) | Anti-Human NGF Recombinant Antibody scFv Fragment (TAB-501MZ-S(P)) | ELISA, IRMA, RIA, IHC | Humanized antibody |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-659 | Human Anti-NGF Recombinant Antibody (clone APE1531); Fab Fragment | WB, FuncS | Human Fab |
| HPAB-0688-CN-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-0688-CN-F(E)) | WB, ELISA | Human Fab |
| HPAB-0515LY-F(E) | Human Anti-NGF Recombinant Antibody (clone H26L17); Fab Fragment | ELISA | Human Fab |
| HPAB-AP153-YC-F(E) | Canine Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-AP153-YC-F(E)) | ELISA, FuncS | Canine Fab |
| HPAB-AP154-YC-F(E) | Canine Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-AP154-YC-F(E)) | ELISA, FuncS | Canine Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-509MZ | Human Anti-NGF Recombinant Antibody (TAB-509MZ) | ELISA | Chimeric (mouse/human) IgG |
| TAB-509MZ-S(P) | Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-509MZ-S(P)) | ELISA | Mouse scFv |
| TAB-510MZ-S(P) | Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-510MZ-S(P)) | ELISA | Mouse scFv |
| TAB-509MZ-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-509MZ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-510MZ-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-510MZ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-488MZ-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (TAB-488MZ-S(P)) | ELISA | Human scFv |
| TAB-489MZ-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (TAB-489MZ-S(P)) | ELISA | Human scFv |
| TAB-490MZ-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (TAB-490MZ-S(P)) | ELISA | Human scFv |
| TAB-491MZ-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (TAB-491MZ-S(P)) | ELISA | Human scFv |
| TAB-492MZ-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (TAB-492MZ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-500MZ-F(E) | Anti-Human NGF Recombinant Antibody Fab Fragment (TAB-500MZ-F(E)) | ELISA, IRMA, RIA, IHC | |
| TAB-502MZ-F(E) | Anti-Dog NGF Recombinant Antibody Fab Fragment (NV-01) | SDS-PAGE | |
| TAB-503MZ-F(E) | Mouse Anti-NGF Recombinant Antibody; Fab Fragment (TAB-503MZ-F(E)) | ELISA | Mouse Fab |
| TAB-504MZ-F(E) | Mouse Anti-NGF Recombinant Antibody; Fab Fragment (TAB-504MZ-F(E)) | ELISA | Mouse Fab |
| TAB-505MZ-F(E) | Mouse Anti-NGF Recombinant Antibody; Fab Fragment (TAB-505MZ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0852MZ | Chicken Anti-NGF Polyclonal IgY | ELISA | Chicken antibody |
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|---|---|---|---|
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|---|---|---|---|
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|---|---|---|---|
| NEUT-1768CQ | Recombinant Mouse Anti-NGF Antibody (aD11) | IF, BL, ELISA, IHC | IgG1, κ |
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|---|---|---|---|
| HPAB-0688-CN | Human Anti-NGF Recombinant Antibody (HPAB-0688-CN) | WB, ELISA | Human IgG4 |
| MRO-2073-CN | Rabbit Anti-NGF Polyclonal Antibody (MRO-2073-CN) | WB, IF, IHC | Rabbit IgG |
| HPAB-0718-FY | Mouse Anti-NGF Recombinant Antibody (clone AB020) | ELISA | Mouse IgG |
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| HPAB-0893-FY | Canine Anti-NGF Recombinant Antibody (HPAB-0893-FY) | ELISA | Canine IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| HPAB-1799LY-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (HPAB-1799LY-S(P)) | ELISA, Neut, FC | Human scFv |
| HPAB-AP153-YC-S(P) | Canine Anti-NGF Recombinant Antibody; scFv Fragment (HPAB-AP153-YC-S(P)) | ELISA, FuncS | Canine scFv |
| HPAB-AP154-YC-S(P) | Canine Anti-NGF Recombinant Antibody; scFv Fragment (HPAB-AP154-YC-S(P)) | ELISA, FuncS | Canine scFv |
| HPAB-AP155-YC-S(P) | Canine Anti-NGF Recombinant Antibody; scFv Fragment (HPAB-AP155-YC-S(P)) | ELISA, FuncS | Canine scFv |
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| CAT | Product Name | Application | Type |
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