Human Anti-PCSK9 Recombinant Antibody (clone 2.12.12.4-z4-uIgG4K) (CAT#: HPAB-N0206-YC)
Provided is a monoclonal antibody for a proprotein convertase subtilisin Kexin 9 (PCSK9). The monoclonal antibody can block the binding of PCSK9 to a LDL receptor so that the level of LDL-C is reduced. The monoclonal antibody provides a very effective agent for treating various CVD diseases.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A-431, CACO-2, HaCaT, HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169174-PCSK9
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169174-PCSK9
Specifications
- Host Species
- Human
- Type
- Human IgG4, κ
- Specificity
- Human PCSK9
- Species Reactivity
- Human, Cynomolgus
- Clone
- 2.12.12.4-z4-uIgG4K
- Applications
- ELISA, Block
- Related Disease
- Cvd Diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Proprotein Convertase Subtilisin/Kexin Type 9; Subtilisin/Kexin-Like Protease PC9; NARC-1; NARC1; PC9; Convertase Subtilisin/Kexin Type 9 Preproprotein; Hypercholesterolemia, Autosomal Dominant 3; Neural Apoptosis Regulated Convertase 1; Neural Apoptosis-Regulated Convertase 1
- Gene ID
- 255738
- UniProt ID
- Q8NBP7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-294 | Human Anti-PCSK9 Recombinant Antibody (clone mAb1) | WB, Block, FuncS | Human IgG |
| PABL-676 | Human Anti-PCSK9 Recombinant Antibody (PABL-676) | WB, FuncS | Human IgG |
| PABL-677 | Mouse Anti-PCSK9 Recombinant Antibody (clone mAb J16) | WB, ELISA, FuncS | Mouse IgG |
| PABL-678 | Human Anti-PCSK9 Recombinant Antibody (clone CBL21Q) | ELISA, WB | Human IgG |
| PABC-505 | Human Anti-PCSK9 Recombinant Antibody (clone 5E11) | WB, IP, ELISA, IF, Inhib | Human IgG1, λ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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