Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CNTF (CAT#: ACFP-CQ1169)

• Target
• PD-L1

• Molecule Class
• IgG-CNTF

• Species Reactivity
• Human

• Expression Host
• CHO

• Clone
• PD1-AB1

• Cytokine 1
• CNTF

• Cytokines 1 Description
• CNTF (Ciliary Neurotrophic Factor) is a Protein Coding gene. Diseases associated with CNTF include Motor Neuron Disease and Epilepsy, Familial Temporal Lobe, 2. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include growth factor activity and ciliary neurotrophic factor receptor binding.

• Cytokine 1 Species
• Human

• Applications
• This product can be used therapeutically to deliver biologically active ligands to a desired tissue.

• Introduction
• This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation.

• Alternative Names
• CD274; PD-L1; PDCD1L1; B7-H; Programmed Death Ligand 1; Programmed Cell Death 1 Ligand 1; PDCD1LG1; B7H1

• Gene ID
• 29126

• UniProt ID
• Q9NZQ7

• TAB-0190CL
• Anti-Human CD274 Recombinant Antibody (PD1-AB1)

• TAB-0190CL-S(P)
• Anti-Human CD274 Recombinant Antibody scFv Fragment (PD1-AB1)

• TAB-0190CL-F(E)
• Anti-Human CD274 Recombinant Antibody Fab Fragment (PD1-AB1)

• ACFP-CQ0371
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CCL18

• ACFP-CQ0030
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-IL2

• ACFP-CQ1211
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CSF1

• ACFP-CQ2093
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-IFNA1

• ACFP-CQ0833
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CCL28

• ACFP-CQ0413
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CCL19

• ACFP-CQ1673
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CXCL16

• ACFP-CQ0077
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CCL1

• ACFP-CQ1253
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CSF2

• ACFP-CQ2135
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-IFNA10

• ACFP-CQ0455
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CCL2

• ACFP-CQ0875
• Anti-PD-L1 Antibody-Cytokine Fusion Protein, IgG (PD1-AB1)-CCL3

Select a product category from the dropdown menu below to view related products.