Mouse Anti-TNFSF11 Recombinant Antibody (clone 4F4); Fab Fragment

CAT#: HPAB-AP837-YC-F(E)

The RANKL- specific antibody is an antibody specifically binding to RANKL of human and mouse. It can be usefully utilized in the preclinical and clinical studies. In addition, by inhibiting the RANKL activity of promoting the differentiation of osteoclasts, by inhibiting the osteoclast differentiation, it is possible to treat bone-related diseases which are caused by the imbalance of osteoclasts and can be widely utilized in the therapeutic development of bone-related disorders.

Gene Expression
Figure 1 High expression in lymph node Figure 2 Low expression in cerebral cortex Figure 3 IHC staining of human bone marrow Figure 4 Lymph node Figure 5 RNA cell line category: Cell line enhanced (HSkMC, NTERA-2)

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse Fab
  • Specificity
  • Human TNFSF11
  • Species Reactivity
  • Human, Mouse
  • Clone
  • 4F4
  • Related Disease
  • Development of bone-related disorders

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • TNF Superfamily Member 11; Tumor Necrosis Factor (Ligand) Superfamily, Member 11; TNF-Related Activation-Induced Cytokine; Osteoclast Differentiation Factor; Osteoprotegerin Ligand; TRANCE; RANKL; OPGL; ODF; Receptor Activator Of Nuclear Factor Kappa B Ligand; Receptor Activator Of Nuclear Factor Kappa-B Ligand
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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