CD28 & melanoma-associated proteoglycan
Anti-CD28 & melanoma-associated proteoglycan Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: FC, FuncS, Neut, WB
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- Species Reactivity: Mouse
- Type: Hamster IgG
- Application: IHC-Fr, FC, IP, Block, FuncS
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- Species Reactivity: Mouse
- Type: Mouse IgG2b, κ
- Application: FC, Costim, Block
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- Species Reactivity: Mouse
- Type: Hamster IgG1
- Application: Neut
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- Species Reactivity: Mouse
- Type: Hamster IgG
- Application: ELISA, FC, Neut
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, FC, IP, FuncS, IF, Neut
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- Species Reactivity: Mouse
- Type: Mouse IgG1, kappa
- Application: FC, IHC, Costim, Agonistic assays, SPR
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Agonistic assays
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, Agonistic assays
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: FC, Agonistic assays, CyTOF®
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- Species Reactivity: Rat
- Type: Rabbit IgG, kappa
- Application: FC, IF, IHC, Costim, Agonistic assays
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- Species Reactivity: Rat
- Type: Mouse IgG1, kappa
- Application: FC, IF, IHC, Costim, Agonistic assays
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- Species Reactivity: Mouse
- Type: Rabbit IgG, kappa
- Application: FC, IHC, Costim, Agonistic assays, SPR
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For Research Use Only. Not For Clinical Use.
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
CD28 (CD28 Molecule) is a Protein Coding gene. Diseases associated with CD28 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are Th2 Differentiation Pathway and RET signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and SH3/SH2 adaptor activity. An important paralog of this gene is CTLA4.