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For Research Use Only. Not For Clinical Use.
Cancer-related genes, Enzymes
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Monomer. Interacts with ARRB2 (By similarity). Interacts with AXIN1 and CTNNB1/beta-catenin (PubMed:17229088). Interacts with CTNND2 (PubMed:19706605). Interacts with LMBR1L (PubMed:31073040). Interacts with DDX3X (PubMed:18846110). Interacts with TNFRSF10B (PubMed:18846110). Interacts with RICTOR; the interaction results in phosphorylation of RICTOR at 'Thr-1695' by GSK3A which facilitates FBXW7-mediated ubiquitination and subsequent degradation of RICTOR (PubMed:25897075). (Microbial infection) Interacts with M.tuberculosis PtpA.
Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase