Recombinant monoclonal antibody to EGFR. Tomuzotuximab is a chimeric monoclonal antibody that can be potentially used in the treatment of Cancers, head and neck, Solid tumors.
Figure 1 Concentration-time profiles of repeated weekly infusions of (A) 720 mg and (B) 990 mg tomuzotuximab measured in individual patients before and at the end of infusion.
The dotted line indicates the 50 µg/mL trough level. Tomuzotuximab serum levels were above 50 µg/mL 1 week after the second infusion in four out of five patients who received 720 mg and 1 week after the first infusion in all three patients who received 900 mg tomuzotuximab.
Fiedler, W., Cresta, S., Schulze-Bergkamen, H., De Dosso, S., Weidmann, J., Tessari, A., ... & Zurlo, A. (2018). Phase I study of tomuzotuximab, a glycoengineered therapeutic antibody against the epidermal growth factor receptor, in patients with advanced carcinomas. ESMO open, 3(2), e000303.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Afuco™ Anti-EGFR ADCC Recombinant Antibody (Tomuzotuximab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to EGFR. Tomuzotuximab is a chimeric monoclonal antibody that can be potentially used in the treatment of Cancers, head and neck, Solid tumors.
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