Mouse Anti-IL6 Recombinant Antibody (clone 7C10C6 ) (CAT#: VS7-0425-WR141)
This product is a mouse IgG2b recombinant antibody that binds to human IL6. The antibody 7C10C6 can be used for IHC and FC assays. It cross reacts with mouse and rat and and rabbit.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72821/1350_G7_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72821/1350_G7_3_selected.jpg
Figure 2 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows distinct cytoplasmic positivity in subsets of immune cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_8_2_selected.jpg
(Immunohistochemical staining of human duodenum shows distinct cytoplasmic positivity in subsets of immune cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_8_2_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_B_7_5.jpg
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_B_7_5.jpg
Figure 4 Urinary bladder
(Urothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_4_5.jpg
(Urothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_4_5.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_9_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_9_8.jpg
Figure 6 RNA cell line category: Group enriched (BJ hTERT+, GAMG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136244-IL6
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136244-IL6
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human IL6
- Species Reactivity
- Human, Mouse, Rat, Rabbit
- Clone
- 7C10C6
- Molecule Class
- Cytokine
- Applications
- IHC, FC
- Conjugate
- Unconjugated
- Related Disease
- Rheumatoid arthritis; Inflammatory bowel disease (IBD); Systemic lupus erythematosus (SLE); Multiple myeloma and other cancers; Atherosclerosis; Sepsis; COVID-19; Osteoporosis; Pregnancy complications
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
- Gene ID
- 3569
- UniProt ID
- P05231
- Long Name
- Interleukin 6
- Cellular Localization
- Secreted
- Post Translation Modifications
- N- and O-glycosylated.
- Protein Refseq
- NP_000591
- Function
- cytokine activity; cytokine activity; growth factor activity; interleukin-6 receptor binding; contributes_to interleukin-6 receptor binding; interleukin-6 receptor binding;
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Related Resources
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Graft-versus-Host Disease
AGE-RAGE Signaling Pathway in Diabetic Complications
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-239 | Anti-Human IL6 Recombinant Antibody (TAB-239) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 |
| TAB-0022CL-F(E) | Mouse Anti-IL6 Recombinant Antibody; Fab Fragment (TAB-0022CL-F(E)) | Elisa, In vivo, FuncS, Block | Mouse Fab |
| TAB-0023CL-F(E) | Mouse Anti-IL6 Recombinant Antibody; Fab Fragment (TAB-0023CL-F(E)) | Elisa, In vivo, FuncS, Block | Mouse Fab |
| TAB-0024CL-F(E) | Mouse Anti-IL6 Recombinant Antibody; Fab Fragment (TAB-0024CL-F(E)) | Elisa, In vivo, FuncS, Block | Mouse Fab |
| TAB-0025CL-F(E) | Mouse Anti-IL6 Recombinant Antibody; Fab Fragment (TAB-0025CL-F(E)) | Elisa, In vivo, FuncS, Block | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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