Mouse Anti-IL1B Recombinant Antibody (clone mumAb) (CAT#: VS-0324-QX10)
lnterleukin-1 beta (IL-1B), also known as catabolin, is a cytokine protein. IL-1B is a member of the interleukin 1 family of cytokines.
This antibody binds to human, cynomolgus, rabbit, rat, and mouse IL-1beta and inhibits the interaction between IL-1beta and the human IL-1 receptors I and II. This antibody binds mouse IL-1B with a binding affinity of Kd= 0.49 nM.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Specifications
- Immunogen
- Human recombinant IL-1beta
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Human, cynomolgus, rabbit, rat, and mouse IL-1beta
- Species Reactivity
- Human, Mouse, Cynomolgus, Rabbit, Rat
- Clone
- mumAb
- Applications
- Inhib, ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- IL-1; IL1F2; IL1-BETA
- Gene ID
- 3553
- UniProt ID
- P01584
- Long Name
- Interleukin-1 beta
- Sequence Similarities
- Belongs to the IL-1 family.
- Cellular Localization
- Cytoplasm, cytosol. Lysosome. Secreted, exosome. Cytoplasmic vesicle, autophagosome. Secreted.
- Post Translation Modifications
- Activation of the IL1B precursor involves a CASP1-catalyzed proteolytic cleavage. Processing and secretion are temporarily associated.
- Function
- Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-239 | Human Anti-IL1B Recombinant Antibody (clone YC129); scFv Fragment | WB, IHC, FuncS | Human scFv |
| HPAB-0330-FY-S(P) | Mouse Anti-IL1B Recombinant Antibody scFv Fragment (HPAB-0330-FY-S(P)) | ELISA, In vivo | Mouse scFv |
| HPAB-0331-FY-S(P) | Mouse Anti-IL1B Recombinant Antibody scFv Fragment (HPAB-0331-FY-S(P)) | ELISA, In vivo | Mouse scFv |
| HPAB-0332-FY-S(P) | Mouse Anti-IL1B Recombinant Antibody scFv Fragment (HPAB-0332-FY-S(P)) | ELISA, In vivo | Mouse scFv |
| HPAB-0333-FY-S(P) | Human Anti-IL1B Recombinant Antibody scFv Fragment (HPAB-0333-FY-S(P)) | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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