Recombinant Mouse Anti-IL1B Detection Antibody (clone 1B3) (CAT#: VS3-WK1673)

This antibody is a mouse recombinant antibody against human IL1B. The sandwich ELISA was established using matched antibody pair 5A11 and 1B3. The clone 1B3 can be used in ELISA analysis as a detection antibody at a dilution of 1/1000. It was developed by immunization of mouse with recombinant human IL1B protein and then was produced as a recombinant antibody. The isotype of this product is mouse IgG3a.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Specifications

  • Immunogen
  • Recombinant human IL1B protein
  • Host Species
  • Mouse
  • Type
  • Mouse IgG3a
  • Specificity
  • Human IL1B
  • Species Reactivity
  • Human
  • Clone
  • 1B3
  • Applications
  • ELISA
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein G affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • 0.01% thimerosal
  • Storage
  • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • ELISA: 1/1000

Target

  • Alternative Names
  • Interleukin 1 Beta
  • Long Name
  • Interleukin 1 Beta
  • Sequence Similarities
  • Belongs to the IL-1 family.
  • Cellular Localization
  • Cytoplasm, Lysosome, Secreted
  • Post Translation Modifications
  • Activation of the IL1B precursor involves a CASP1-catalyzed proteolytic cleavage. Processing and secretion are temporarily associated.
    (Microbial infection) Cleavage by S.pyogenes cysteine protease SpeB promotes its activation independently of CASP1.
  • Function
  • Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.

Recommended Products

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "IL1B"

Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products IgG Antibody Products Fab Antibody Products Chimeric Antibody Products Mouse Antibody Products Human Antibody Products Chicken IgY Antibody Products Neutralizing Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products ADCC Enhanced Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for VS3-WK1673. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare