Afuco™ Anti-IL6 ADCC Recombinant Antibody (Sirukumab), ADCC Enhanced (CAT#: AFC-TAB-097)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL6. Sirukumab (CNTO 136) is a human monoclonal antibody designed for the treatment of rheumatoid arthritis.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Recombinant full length protein (Human).
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Clone
  • Sirukumab
  • Applications
  • FC, IP, ELISA, Neut, FuncS, IF
  • Conjugate
  • Unconjugated
  • Generic Name
  • Sirukumab
  • Related Disease
  • Rheumatoid arthritis (RA) (Despite Methotrexate Therapy)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Sirukumab; 1194585-53-9; CNTO 136; AME-19A; IL6; interleukin 6 (interferon, beta 2); IFNB2; interleukin-6; BSF2; HGF; HSF; IL 6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2;

Related Resources

  • Biosimilar Overview
  • Related Diseases
  • Related Signaling Pathways
Please refer to Sirukumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Sirukumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Sirukumab"

Anti-Human IL6 Recombinant Antibody (Sirukumab)
Recombinant monoclonal antibody to IL6. Sirukumab (CNTO 136) is a human monoclonal antibody designed for the treatment of rheumatoid arthritis.

See other products for "IL6"

Chimeric Antibody

CAT Product Name Application Type
TAB-0026CL Human Anti-IL6 Recombinant Antibody (TAB-0026CL) Elisa, In vivo, FuncS, Block Chimeric (mouse/human) IgG
TAB-0026CL-S(P) Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0026CL-S(P)) Elisa, In vivo, FuncS, Block Mouse scFv
TAB-670LC Anti-human IL6 Recombinant Antibody (NTS) (TAB-670LC) ELISA, Inhib Chimeric antibody (mouse/human)
TAB-670LC-S(P) Anti-human IL6 scFv Fragment (NTS) ELISA Chimeric antibody (mouse/human)
TAB-670LC-F(E) Anti-human IL6 Fab Fragment (NTS) ELISA Chimeric antibody (mouse/human)

Humanized Antibody

Fab Glycosylation

CAT Product Name Application Type
Gly-037LC Recombinant Anti-Human IL6 Antibody (Fab glycosylation) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-197LC Recombinant Anti-Human IL6 Antibody (Non-glycosylated) ELISA Humanized antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0284MZ Chicken Anti-Interleukin-6 Polyclonal IgY WB, Indirect ELISA Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1474CQ Rat Anti-Il6 Recombinant Antibody (clone 32C11) Block, ELISA, WB Rat IgG2a

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1480CQ Rat Anti-Il6 Recombinant Antibody (clone CBL938) ELISA, IHC, IP, Neut Rat IgG1
NEUT-1481CQ Rat Anti-Il6 Recombinant Antibody (clone CBL960) ELISA, FC, IHC, Neut, WB Rat IgG1
NEUT-1482CQ Rat Anti-Il6 Recombinant Antibody (clone 5A37) Neut, WB Rat IgG1
NEUT-1483CQ Rat Anti-Il6 Recombinant Antibody (clone mAb0847) FC, IHC-Fr, IP, Neut Rat IgG1
NEUT-1484CQ Rat Anti-Il6 Recombinant Antibody (clone MP5-20F3) ELISA, CyTOF, ELISPOT, Neut, IHC Rat IgG1, κ

MHC Tetramer for Cancer

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-239 Afuco™ Anti-IL6 ADCC Recombinant Antibody (Elsilimomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-H26 Afuco™ Anti-IL6 ADCC Recombinant Antibody (Enlimomab), ADCC Enhanced Neut, ELISA, IF, IP, FuncS, FC ADCC enhanced antibody
AFC-TAB-253 Afuco™ Anti-IL6 ADCC Recombinant Antibody (Olokizumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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