Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced (CAT#: AFC-TAB-771)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human MS4A1/CD20. Ocaratuzumab is a humanized monoclonal antibody designed for the treatment of cancer and autoimmune disorders. The antibody is engineered for enhanced affinity to the CD20 antigen on B-lymphocytes, increased antibody-dependent cell-mediated cytotoxicity (ADCC), and for improved treatment of low-affinity FcγRIIIa allotypes.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Clone
  • Ocaratuzumab
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC
  • Conjugate
  • Unconjugated
  • Generic Name
  • Ocaratuzumab
  • Related Disease
  • Non-Hodgkin's lymphoma (NHL)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Ocaratuzumab; 1169956-08-4; AME 33; AME-133v; LY2469298; AME-133v; LY2469298; MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; MS4A2; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16

Related Resources

  • Biosimilar Overview
Please refer to Ocaratuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ocaratuzumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Ocaratuzumab"

See other products for "MS4A1"

Humanized Antibody

CAT Product Name Application Type
TAB-772 Human Anti-MS4A1 Recombinant Antibody (TAB-772) ELISA, IP, FC, FuncS, Neut, IF, ICC IgG1
TAB-771 Humanized Anti-MS4A1 Recombinant Antibody (TAB-771) IF, IP, Neut, FuncS, ELISA, FC, ICC Humanized IgG1, κ
TAB-133 Anti-Human CD20 Recombinant Antibody (Afutuzumab) IP, IF, FuncS, FC, Neut, ELISA, ICC IgG3 - kappa
TAB-1638CL Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) ADCC, CDC Humanized IgG
TAB-1639CL Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) ADCC, CDC, Apop Humanized IgG

Mouse Antibody

CAT Product Name Application Type
TAB-017 Anti-Human CD20 Recombinant Antibody (Tositumomab) Neut, ELISA, IF, IP, FuncS, FC, ICC IgG2a - lambda
TAB-711 Anti-MS4A1 Recombinant Antibody (Technetium (99MTC) Nofetumomab Merpentan) FC, IP, ELISA, Neut, FuncS, IF, ICC Fab - G2b - kappa
TAB-H27 Anti-Human MS4A1 Recombinant Antibody (Epitumomab) IP, IF, FuncS, FC, Neut, ELISA, ICC IgG2a
TAB-H39 Anti-Human MS4A1 Recombinant Antibody (Ibritumomab) FC, IP, ELISA, Neut, FuncS, IF, ICC Mouse IgG1 - kappa
TAB-007ML Anti-Canine MS4A1 Recombinant Antibody (Blontuvetmab) ELISA, IHC, FC, IP, IF, FuncS IgG2, κ, λ

Recombinant Antibody

CAT Product Name Application Type
PABL-422 Human Anti-MS4A1 Recombinant Antibody (clone 2F2) WB, ELISA, FuncS Human IgG1,κ
PABL-423 Mouse Anti-MS4A1 Recombinant Antibody (clone GA101) FC, Activ, Agonist, IF, WB, Cyt, FuncS Mouse IgG
MOB-0279MZ Mouse Anti-MS4A1 Recombinant Antibody (clone M27 (1, 4).) IHC Mouse IgG2a
FAMAB-0241CQ Mouse Anti-MS4A1 Recombinant Antibody (clone 2H7) ELISA, FC, IHC, IP Mouse IgG2b, κ
HPAB-0683-CN Human Anti-MS4A1 Recombinant Antibody (clone Rmut8) ELISA, FC Chimeric (mouse/human) IgG

Fc Glycosylation

Hyper-galactosylated

High-mannose Glycoform

CAT Product Name Application Type
Gly-155LC-1 Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-171LC Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) ELISA Chimeric antibody (mouse/human)

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1751CQ Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) Neut, FuncS Mouse IgG1, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-772 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-016 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-028 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-207 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-H39 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ibritumomab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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