Human Anti-PDCD1 Recombinant Antibody (clone NOV010YC); scFv Fragment

Name: Human Anti-PDCD1 Recombinant Antibody (clone NOV010YC); scFv Fragment
SKU: HPAB-N0217-YC-S(P)
Rating: 5 (1 reviews)

CAT#: HPAB-N0217-YC-S(P)

The anti-human PD-1 monoclonal antibody has good bioactivity, can effectively bind with an extracellular region of PD-1 protein receptor, can effectively seal PD-1 protein at protein level and cellular level and block the binding of the PD-1 protein with ligands PD-L1 and PD-L2, and immunity is effectively enhanced.

Gene Expression

Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg

Normal Tissue Figure 2 Tonsil

Germinal center cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1

❮

❯

Specifications

Host Species
Human

Derivation
Humanized

Type
Humanized scFv

Specificity
Human PDCD1

Species Reactivity
Human

Clone
NOV010YC

Applications
ELISA, FC, Block

Related Disease
Autoimmune Diseases, Tumor

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Programmed Cell Death 1; Systemic Lupus Erythematosus Susceptibility 2; Protein PD-1; HPD-1; PD1; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1

Gene ID
5133

UniProt ID
Q15116

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-N0217-YC-S(P).pdf

MSDS

MSDS - HPAB-N0217-YC-S(P).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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