Recombinant Rabbit Anti-IL1B Detection Antibody (clone R05-7Z7) (CAT#: VS3-WK1759)
This antibody is a rabbit recombinant antibody against mouse IL1B. It was developed by immunization of rabbit with recombinant mouse IL1B protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R02-6W6 and R05-7Z7 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R05-7Z7 can be used in ELISA analysis to identify mouse IL1B.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Specifications
- Immunogen
- Recombinant mouse IL1B protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse IL1B
- Species Reactivity
- Mouse
- Clone
- R05-7Z7
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Il-1b; IL-1beta
- Gene ID
- 16176
- UniProt ID
- P10749
- Long Name
- Interleukin 1 beta
- Sequence Similarities
- Belongs to the IL-1 family.
- Cellular Localization
- Cytoplasm, Lysosome, Secreted
- Protein Refseq
- NP_032387.1
- Function
- Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-021 | Anti-Human IL1Beta Recombinant Antibody (Canakinumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
| TAB-545LC-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-545LC-S(P)) | ELISA, FC | Human scFv |
| TAB-546LC-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-546LC-S(P)) | ELISA, FC | Human scFv |
| TAB-547LC-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-547LC-S(P)) | ELISA, FC | Human scFv |
| TAB-550LC-S(P) | Anti-human IL1B scFv Fragment (9.5.2) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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